Anti-Human CD3 PerCP-Cyanine5.5

Also known as: Leu-4, T3

Clone: SK7

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-0036

Cat. No.	Size
45-0036-41	25 tests
45-0036-42	100 tests
Please inquire about custom configurations or bulk packaging.

To enable ordering, please select your country. Cookies will need to be enabled to continue on our website. View our Privacy Policy.

Staining of normal human peripheral blood cells with Mouse IgG1 K Isotype Control PerCP-Cyanine5.5...View More

Description

Description: The SK7 monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits γ and δ, the ε chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. The SK7 and UCHT1 monoclonal antibodies cross-block binding, suggesting recognition of overlapping epitopes.

The antibody SK7 recognizes chimpanzee CD3.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PerCP-Cyanine5.5
Laser	Blue Laser
Excite	488 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
48-0036	Anti-Human CD3 eFluor® 450	405 nm		FC	RUO
35-0036	Anti-Human CD3 PE-Cyanine5.5	488 - 567 nm	690 nm	FC	RUO
11-0036	Anti-Human CD3 FITC	488 nm		FC	RUO
16-0036	Anti-Human CD3 Functional Grade Purified			FC, FA	RUO
12-0036	Anti-Human CD3 PE	488 - 561 nm		FC	RUO
17-0036	Anti-Human CD3 APC	633 - 647 nm	660 nm	FC	RUO
47-0036	Anti-Human CD3 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
46-0036	Anti-Human CD3 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
45-4714	Mouse IgG1 K Isotype Control PerCP-Cyanine5.5	488 nm		FC	RUO
48-0088	Anti-Human CD8a eFluor® 450	405 nm	450 nm	FC	RUO
93-0048	Anti-Human CD4 eFluor® 605NC	350 - 590 nm	605 nm	FC	RUO

References

References: Kap YS, van Meurs M, van Driel N, Koopman G, Melief MJ, Brok HP, Laman JD, 't Hart BA. A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem. 2009 Dec;57(12):1159-67. (SK7.10, IHC frozen, chimpanzee, PubMed)

van Dongen JJ, Krissansen GW, Wolvers-Tettero IL, Comans-Bitter WM, Adriaansen HJ, Hooijkaas H, van Wering ER, Terhorst C. Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies.Blood. 1988 Mar;71(3):603-12

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD3	Adaptive Immunity Cell Signaling	NK & NKT Cells T Cells Th17 Cells Treg Cells	PerCP-Cyanine5.5