Anti-Human CD3 PE-Cyanine5.5

Also known as: Leu-4, T3

Clone: SK7

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 35-0036

Cat. No.	Size
35-0036-41	25 tests
35-0036-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells with Anti-Human CD19 APC (cat. 17-0199) and Mouse...View More

Description

Description: The SK7 monoclonal antibody reacts with human and chimpanzee CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. The SK7 and UCHT1 monoclonal antibodies cross-block binding, suggesting recognition of overlapping epitopes.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine5.5
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	690 nm
Excite	488 - 567 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT# 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
17-0036	Anti-Human CD3 APC	633 - 647 nm	660 nm	FC	RUO
16-0036	Anti-Human CD3 Functional Grade Purified			FC, FA	RUO
47-0036	Anti-Human CD3 APC-eFluor® 780	633 - 647 nm	780 nm	FC	RUO
48-0036	Anti-Human CD3 eFluor® 450	405 nm		FC	RUO
12-0036	Anti-Human CD3 PE	488 - 561 nm		FC	RUO
45-0036	Anti-Human CD3 PerCP-Cyanine5.5	488 nm		FC	RUO
11-0036	Anti-Human CD3 FITC	488 nm		FC	RUO
46-0036	Anti-Human CD3 PerCP-eFluor® 710	488 nm	710 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-4222	Flow Cytometry Staining Buffer			FC	GPR
17-0199	Anti-Human CD19 APC	633 - 647 nm	660 nm	FC	RUO
35-4714	Mouse IgG1 K Isotype Control PE-Cyanine5.5	488 - 567 nm	690 nm	FC	RUO

References

References: Kap YS, van Meurs M, van Driel N, Koopman G, Melief MJ, Brok HP, Laman JD, 't Hart BA. A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem. 2009 Dec;57(12):1159-67. (SK7, IHC frozen, chimpanzee, PubMed)

van Dongen JJ, Krissansen GW, Wolvers-Tettero IL, Comans-Bitter WM, Adriaansen HJ, Hooijkaas H, van Wering ER, Terhorst C. Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies. Blood. 1988 Mar;71(3):603-12

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD3	Adaptive Immunity Cell Signaling	NK & NKT Cells T Cells Th17 Cells Treg Cells	PE-Cyanine5.5