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Anti-Human CD3 Functional Grade Purified

Also known as: Leu-4, T3

Clone: HIT3a

RUO: For Research Use Only. Not for use in diagnostic procedures.

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SKU# 16-0039

Cat. No. Size
16-0039-81 50 ug
16-0039-85 500 ug

Data for Anti-Human CD3 Functional Grade Purified.

Staining of normal human peripheral blood cells with Anti-Human CD3 PE. Autofluorescence is...View More

  • Data for Anti-Human CD3 Functional Grade Purified.
Description

Description: The HIT3a monoclonal antibody reacts with human CD3e, a 20 kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR with HIT3a initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.

Details
Host Mouse
Isotype IgG2a, kappa
Reactivity Human
Reported Applications Flow Cytometric Analysis, Functional Assays
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-0039 Anti-Human CD3 Purified FC RUO
12-0039 Anti-Human CD3 PE 488 - 561 nm 578 nm FC RUO
11-0039 Anti-Human CD3 FITC 488 nm 520 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
13-4013 Anti-Mouse IgG Biotin FC, ELISA, IHC, WB RUO
16-4724 Mouse IgG2a K Isotype Control Functional Grade Purified FC RUO
References

References: McMichael, A. J., P.C.L. Beverly, et al. eds. (1987). Leucocyte Typing III: White Cell Differentiation Antigens. Oxford University Press. New York.

Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.

Schlossman, S., L. Bloumsell, et al. eds (1995). Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.