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  • Anti-Human CD244 Alexa Fluor® 647 (Discontinued. Refer to Alternative Format: APC, cat. 17-5837)

Anti-Human CD244 Alexa Fluor® 647 (Discontinued. Refer to Alternative Format: APC, cat. 17-5837)

Also known as: 2B4, p38, SLAMF4, NKLR2B4

Clone: eBioDM244

RUO: For Research Use Only. Not for use in diagnostic procedures.

Attention: Discontinued. Refer to Replacement Format APC cat. 17-5837

SKU# 51-5837

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Data for Anti-Human CD244 Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC, cat. 17-5837).

Staining of normal human peripheral blood cells with Anti-Human CD56 (NCAM) FITC (cat. 11-0569)...View More

  • Data for Anti-Human CD244 Alexa Fluor® 647 (To Be Discontinued. Refer to Alternative Format: APC, cat. 17-5837).
Description

Description: The eBioDM244 monoclonal antibody reacts with human CD244 (2B4, p38). In human, CD244 is a 38 kDa protein expressed on NK cells, a subset of CD8+ T cells, γδ T cells, monocytes, basophils and eosinophils. Binding of the CD244 ligand, CD48, results in NK cell activation, unlike mouse CD244, which is an inhibitory receptor.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate Alexa Fluor 647
Laser Red Laser
Emit 668 nm
Excite 633 nm
Legal Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
17-5837 Anti-Human CD244 APC 633 - 647 nm 660 nm FC RUO
11-5837 Anti-Human CD244 FITC 488 nm 518 nm FC RUO
References

References: Boles KS, Nakajima H, Colonna M, Chuang SS, Stepp SE, Bennett M, Kumar V, Mathew PA. Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4.Tissue Antigens. 1999 Jul;54(1):27-34.

Tangye SG, Cherwinski H, Lanier LL, Phillips JH. 2B4-mediated activation of human natural killer cells.Mol Immunol. 2000 Jun;37(9):493-501.

Sivori S, Falco M, Marcenaro E, Parolini S, Biassoni R, Bottino C, Moretta L, Moretta A. Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation.Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4526-31.

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