CD21 eFluor® 450

Also known as: CR2, Complement Component 3d Receptor (C3DR), EBV Receptor

Clone: HB5

Analyte Specific Reagent (ASR): Analytical and performance characteristics are not established.

SKU# 8048-0219

Cat. No.	Size
8048-0219-120	120 tests
8048-0219-025	25 tests
Please inquire about custom configurations or bulk packaging.

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Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More

Description

Description: The HB5 monoclonal antibody reacts with human CD21, an approximately 145 kDa type I transmembrane protein. CD21 is expressed by mature B cells, follicular dendritic cells and a subset of epithelial cells. It is a receptor for complement component C3d and Epstein-Barr virus (EBV). CD21, in association with CD19 and CD81, participates in the multimolecular complex with the B cell receptor (BCR) and is involved in B cell activation.

Details

Host	Mouse
Isotype	IgG2a, kappa
Reactivity	Human
Conjugate	eFluor 450
Laser	Violet Laser
Emit	450 nm
Excite	405 nm

Documentation

TDS Link	Download TDS

References

References: Tedder TF, Clement LT, Cooper MD. Expression of C3d receptors during human B cell differentiation: Immunofluorescence analysis with the HB-5 monoclonal antibody. J. Immunol. 1984; 133:678-683.

Tedder TF, Clement LT, Weis JJ, Fearon DT, Cooper MD. The C3d receptor identified by the HB-5 monoclonal antibody: Expression and Role as a receptor for Epstein-Barr virus. Leukocyte Typing II. 1986; 2:499-508.

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Antigens	Cell Type	Formats
CD21	B Cells	eFluor 450