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Anti-Human CD21 APC

Also known as: CR2, Complement Component 3d Receptor (C3DR), EBV Receptor, EBV-R

Clone: HB5

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 17-0219

Cat. No. Size
17-0219-42 100 tests
17-0219-41 25 tests
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Data for Anti-Human CD21 APC.

Staining of normal human peripheral blood cells with Anti-Human CD3 FITC (cat. 11-0038) and Mouse...View More

  • Data for Anti-Human CD21 APC.
Description

Description: The HB5 monoclonal antibody reacts with human CD21, an approximately 145 kDa type I transmembrane protein. CD21 is expressed by mature B cells, folliculate dendritic cells and a subset of epithelial cells and is a receptor for complement component C3d and Epstein-Barr virus (EBV). CD21, in association with CD19 and CD81, participates in the multimolecular complex with BCR and is involved in B cell activation.

Details
Host Mouse
Isotype IgG2a, kappa
Reactivity Human
Conjugate APC
Laser Red Laser
Emit 660 nm
Excite 633 - 647 nm
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
12-0219 Anti-Human CD21 PE 488 - 561 nm 575 nm FC RUO
References

References: Tedder TF, Clement LT, Cooper MD. Expression of C3d receptors during human B cell differentiation: Immunofluorescence analysis with the HB-5 monoclonal antibody. J. Immunol. 1984; 133:678-683.

Tedder TF, Clement LT, Weis JJ, Fearon DT, Cooper MD. The C3d receptor identified by the HB-5 monoclonal antibody: Expression and Role as a receptor for Epstein-Barr virus. Leukocyte Typing II. 1986; 2:499-508.

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