Anti-Human CD209 (DC-SIGN) PerCP-Cy5.5

Also known as: CLEC4L, CIRE

Clone: eB-h209

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-2099

Cat. No.	Size
45-2099-41	25 tests
45-2099-42	100 tests

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Description

Description: The eB-h209 monoclonal antibody reacts with human CD209, also known as DC-SIGN, a 44 kDa type II transmembrane protein. DC-SIGN contains a C-type lectin binding domain and binds ICAM-3, ICAM-2, and HIV virus. Human dendritic cells preferentially express DC-SIGN. It has been postulated that DC-SIGN serves as a receptor for capture, trafficking, and transmission of HIV to T cells and supports primary immune response. eB-h209 was developed against a C-terminal peptide of human DC-SIGN.

Details

Host	Rat
Isotype	IgG2a, kappa
Reactivity	Human
Conjugate	PerCP-Cy5.5
Laser	Blue Laser
Emit	690 nm
Excite	488 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
17-2099	Anti-Human CD209 (DC-SIGN) APC	633 nm	660 nm	FC	RUO
13-2099	Anti-Human CD209 (DC-SIGN) Biotin			FC	RUO
12-2099	Anti-Human CD209 (DC-SIGN) PE	488 nm	575 nm	FC	RUO
11-2099	Anti-Human CD209 (DC-SIGN) FITC	488 nm	518 nm	FC	RUO
25-2099	Anti-Human CD209 (DC-SIGN) PE-Cy7	488 nm	760 nm	FC	RUO
14-2099	Anti-Human CD209 (DC-SIGN) Purified			FC, IP	RUO

References

References: Pohlmann, S, F Baribaud, et al. (2001). DC-SIGN Interactions with Human Immunodeficiency Virus type 1 and 2 and Simian Immunodeficiency Virus. J Virol. 75(10):4664-4672

Geijtenbeek, T.B, D.S. Douglas, et al. (2000) DC-SIGN, a Dendritic Cell-Specific HIV-1-Binding protein that Enhances trans-Infection of T cells. Cell 100(5): 587-597.

Geijtenbeek, T.B, R Torensma, et al. (2000). Identification of DC-SIGN, a Novel Dendritic Cell-Specific ICAM-3 Receptor that Supports Primary Immune Responses. Cell 100(5): 575-585.

Geijtenbeek, T.B, D.J. Krooshop, et al. (2000). DC-SIGN-ICAM-2 Interaction Mediates Dendritic Cell Trafficking. Nat. Immunol. 1(4):353-357.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD209 (DC-SIGN)	Innate Immunity	B Cells Dendritic Cells	PerCP-Cy5.5