CD20 eFluor® 450

Description: The 2H7 monoclonal antibody reacts with human CD20, a 33-36 kDa transmembrane protein. CD20 is expressed by developing B cells as well as mature B cells but not plasma cells. CD20 has been detected at low levels on a small subset of mature T cells. It is suggested that CD20 plays a role in B-cell activation.

References: Reinherz EL, et al. eds. Leukocyte Typing II (Vol. I, II, and III). Human Leukocyte Differentiation Antigens detected by Monoclonal Antibodies. 1985.

McMichael AJ, Beverly PCL, et al. eds. Leucocyte Typing III: White Cell Differentiation Antigens. Oxford University Press. New York. 1987.

Knapp W, Dorken B, et al. eds. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. 1989.

Schlossman S, Bloumsell L, et al. eds. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 1995.

Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.