Anti-Human CD1a PE

Description: The SK9 monoclonal antibody reacts with human CD1a, a 49 kDa protein expressed by cortical thymocytes and dendritic cells including Langerhans cells. The CD1 family of proteins share some structural and functional characteristics with the MHC class I molecules; however, members of the CD1 family are not polymorphic. Similar to MHC class I, CD1a associates with the β2-microglobulin and is thought to play a role in antigen presentation.

References:
Schmitt, D., C. Dezutter-Dambuyant, et al. eds. (1986). Subclustering of CD1 Monoclonal Antibodies Based on the Reactivity on Human Langerhans Cells. Immunology Letters. France.