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Anti-Human CD197 (CCR7) Purified

Also known as: C-C chemokine receptor type 7, EBI-1, CCR-7, MIP-3 beta Receptor, CMKBR7

Clone: CCR7.6B3

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 14-9977

Cat. No. Size
14-9977-80 25 ug
14-9977-82 100 ug
Please inquire about custom configurations or bulk packaging.

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Data for Anti-Human CD197 (CCR7) Purified.

Staining of prelysed normal human peripheral blood cells with Anti-Human CD197 (CCR7) Purified...View More

  • Data for Anti-Human CD197 (CCR7) Purified.
Description

Description: The CCR7.6B3 monoclonal antibody reacts with human CCR7, also known as EBI-1 and CD197. CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine) and MIP-3β/ELC (EBI1-ligand chemokine). CCR7 is expressed predominantly on naive T cells characterized as CD45RA+CCR7+ in both CD4 and CD8 populations in peripheral blood as well as on dendritic cells.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate Purified
Reported Applications Flow Cytometric Analysis
Documentation

For complete product information, please download the TDS or IFU document.

TDS Link Download TDS
Additional Formats
References

References:
Hasegawa, H., T. Nomura, et al. 2000. Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells. Blood 95(1): 30-8.

Hirose J, Kawashima H, et al. 2002. Chondroitin sulfate B exerts its inhibitory effect on secondary lymphoid tissue chemokine (SLC) by binding to the C-terminus of SLC. Biochim Biophys Acta. 1571(3):219-24. (FC, PubMed)

Hasegawa H, Nomura T, et al. 2000. Increased chemokine receptor CCR7/EBI1 expression enhances the infiltration of lymphoid organs by adult T-cell leukemia cells. Blood 95(1):30-8. (FC, PubMed)

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