CD19 PE-Cy7

Also known as: Leu-12

Clone: SJ25C1

CE

SKU# 9025-0198

Cat. No.	Size
9025-0198-025	25 tests
9025-0198-120	120 tests
Please inquire about custom configurations or bulk packaging.

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Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More

Description

Description: The SJ25C1 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express this molecule. CD19, along with CD21, CD81, Leu13, and MHC class II, form a multimolecular complex that associates with the BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser
Emit	760 nm
Excite	488 nm
Legal	For research (not to include in vivo research) and/or in vitro diagnostic use only. The only permitted commercial use is provision of research (not to include in vivo research) services and/or in vitro diagnostic services. Not for therapeutic or in vivo applications. Other use needs licenses which are available from GE Healthcare Bio-Sciences Corp. Under U.S. patent nos. Nos 5,268,486, 5,569,587 and 5,627,027 and foreign equivalents and pending applications. This product is subject to proprietary rights of GE Healthcare Bio-Sciences Corp. (“GE Healthcare”) and Carnegie Mellon University (“CMU”) and made and sold under license from GE Healthcare. The product bearing this label is licensed for sale only for research (not to include in vivo research) and in addition may be used to perform research (not to include in vivo research) and/or in vitro diagnostic services for third parties. It is not licensed nor are there any implied licenses for any other use including, without limitation, commercial uses unless expressly authorized by GE Healthcare in writing. If you intend to use this product commercially and you do not have a license to use this product for the intended commercial purpose, return this product, unopened to eBioscience, Inc. 10255 Science Center Drive, San Diego, California 92121 USA and any money paid for the product will be refunded.
Reported Applications	Flow Cytometric Analysis

Documentation

Instructions for Use (English)	Download English IFU
Instructions for Use (French)	Download French IFU
Instructions for Use (German)	Download German IFU
Instructions for Use (Italian)	Download Italian IFU
Instructions for Use (Spanish)	Download Spanish IFU

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
9045-0198	CD19 PerCP-Cy5.5	488 nm	690 nm	FC	CE
9046-0198	CD19 PerCP-eFluor® 710	488 nm	710 nm	FC	CE
9017-0198	CD19 APC	633 - 647 nm	660 nm	FC	CE
9047-0198	CD19 APC-eFluor® 780	633 - 647 nm	780 nm	FC	CE
9012-0198	CD19 PE	488 nm	575 nm	FC	CE
9048-0198	CD19 eFluor® 450	405 nm	450 nm	FC	CE
9043-0198	CD19 PerCP	488 nm		FC	CE

References

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Knapp W, Dorken B, et al, eds. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York. 1989.

Schlossman S, Bloumsell L, et al, eds. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 1995.

Moldenhauer G, Dörken B, Schwartz R, Pezzutto A, Knops J, Hammerling GJ. Analysis of ten Blymphocyte-specific workshop monoclonal antibodies. In: Reinherz EL, Haynes BF, Nadler LM,Bernstein ID, eds. Leukocyte Typing II: Human B Lymphocytes. Vol 2. New York, NY: Springer-Verlag;1986:61-67.

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Antigens	Cell Type
CD19	B Cells