Anti-Human CD144 (VE-Cadherin) Alexa Fluor® 488

Also known as: Cadherin 5

Clone: 16B1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 53-1449

Cat. No.	Size
53-1449-41	25 tests
53-1449-42	100 tests
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Staining of Human Umbilical Vein Endothelial Cells (HUVEC) with Mouse IgG1 K Isotype Control Alexa...View More

Description

Description: The 16B1 antibody reacts with human CD144, also known as VE-cadherin and cadherin-5. The cadherin family of receptors, which are calcium-dependent adhesion molecules, is known to be involved in homophilic cell interactions. VE-cadherin, which is 140 kDa, is localized at the intercellular boundaries of endothelial cells in blood and lymphatic vessels in several tissues. It is thought to play a role in vascular permeability and remodeling.

Details

Host	Mouse
Isotype	IgG1
Reactivity	Human
Conjugate	Alexa Fluor 488
Laser	Blue Laser
Emit	519 nm
Excite	488 nm
Legal	Alexa Fluor® and Pacific Blue® are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. This product is subject to an agreement between Molecular Probes, Inc. and eBioscience, and the manufacture, use, sale or import of this product may be subject to one or more U.S. patents, pending applications and corresponding foreign equivalents, owned by Molecular Probes, Inc. (a wholly owned subsidiary of Invitrogen Corp). The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product for life science research or as an ASR. The buyer cannot use this product for manufacturing or for any other screening (specifically including use in combination with microarrays or High Content Screening) or testing purpose, other than as an ASR. For information on purchasing a license to this product for purposes other than life science research or use as an ASR, contact Molecular Probes, Inc.
Reported Applications	Flow Cytometric Analysis, Immunocytochemistry

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
13-1449	Anti-Human CD144 (VE-Cadherin) Biotin			FC, ICC	RUO
46-1449	Anti-Human CD144 (VE-Cadherin) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
17-1449	Anti-Human CD144 (VE-Cadherin) APC	633 - 647 nm	660 nm	FC	RUO
14-1449	Anti-Human CD144 (VE-Cadherin) Purified			FC, ICC, WB	RUO
56-1449	Anti-Human CD144 (VE-Cadherin) Alexa Fluor® 700	633 - 647 nm	723 nm	FC	RUO
12-1449	Anti-Human CD144 (VE-Cadherin) PE	488 - 561 nm	575 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
53-4714	Mouse IgG1 K Isotype Control Alexa Fluor® 488	488 nm	519 nm	FC, ICC, IHC	RUO

References

References: Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007 Feb;25(2):490-9. (16B1, Immunocytofluorescence, PubMed)

Suzuki S, Sano K, and Tanihara H. 1991. Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue. Cell Regul 2: 261-270.

Breviario F, Caveda L, Corada M, Martin-Padura I, Navarro P, Golay J, Introna M, Gulino D, Lampugnani MG, and Dejana E. 1995. Functional properties of human vascular endothelial cadherin (7B4/Cadherin-5), an endothelium-specific cadherin. Arterioscler Thromb Vasc Biol 15: 1229-1239.

Vincent PA, Xiao K, Buckley KM, and Kowalczyk AP. 2004. VE-Cadherin: adhesion at arm's length. Am J Physiol Cell Physiol 286: 987-997.

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD144 (VE-Cadherin)	Adhesion & Migration Angiogenesis	Hematopoietic Stem Cells Mesenchymal Stem Cells	Alexa Fluor 488