Anti-Human CD14 PE

Description: The 61D3 monoclonal antibody reacts with human CD14, a 53-55 kDa GPI-linked glycoprotein. CD14 is expressed on monocytes, interfollicular macrophages and some dendritic cells. Complexes of LPS and LBP (LPS-Binding Protein) bind with high affinity to monocytes through the surface CD14.

References: Fadok VA, Warner ML, Bratton DL, Henson PM. CD36 is required for phagocytosis of apoptotic cells by human macrophages that use either a phosphatidylserine receptor or the vitronectin receptor (alpha v beta 3). J Immunol 1998 Dec 1;161(11):6250-7.

Kishimoto, T., A.E.G., von dem Borne, et al. eds. 1998 Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing Inc. London.

Schlossman, S., L. Bloumsell, et al. eds 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.