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  • Anti-Human CD123 PerCP-Cyanine5.5

Anti-Human CD123 PerCP-Cyanine5.5

Also known as: Interleukin-3 Receptor alpha, IL-3Ra

Clone: 6H6

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 45-1239

Cat. No. Size
45-1239-42 100 tests
45-1239-41 25 tests
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Data for Anti-Human CD123 PerCP-Cy5.5.

Staining of normal human peripheral blood cells with Anti-Human CD85g (ILT7) Alexa Fluor® 647 and...View More

  • Data for Anti-Human CD123 PerCP-Cy5.5.
Description

Description: The 6H6 monoclonal antibody reacts with human CD123, the α chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common β chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Conjugate PerCP-Cyanine5.5
Laser Blue Laser
Excite 488 nm
Legal FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-1239 Anti-Human CD123 Purified FC, IHC RUO
15-1239 Anti-Human CD123 PE-Cyanine5 488 - 561 nm FC RUO
12-1239 Anti-Human CD123 PE 488 - 561 nm FC RUO
13-1239 Anti-Human CD123 Biotin FC RUO
95-1239 Anti-Human CD123 eFluor® 650NC 350 - 635 nm 650 nm FC RUO
48-1239 Anti-Human CD123 eFluor® 450 405 nm 450 nm FC RUO
11-1239 Anti-Human CD123 FITC 488 nm FC RUO
25-1239 Anti-Human CD123 PE-Cyanine7 488 - 561 nm 775 nm FC RUO
17-1239 Anti-Human CD123 APC 633 - 647 nm 660 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
45-4714 Mouse IgG1 K Isotype Control PerCP-Cyanine5.5 488 nm FC RUO
References

References: Herling, M., M. Teitell, R. Shen, L. Medeiros, and D. Jones. 2003. TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood. 101: 5007-5009.

Jaye, D.L., C.M. Geigerman, et al. 2006. Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+CD56+ hematodermic neoplasms. Mod Pathol. 19(12): 1555-62. (IHC paraffin PubMed)

Peduzzi, E., C. Groeper, et al. 2007. Local activation of the innate immune system in Buruli Ulcer lesions. J Invest Dermatol. 127(3) :638-45. (IHC paraffin PubMed)

Assaf C., S. Gellrich, et al. 2007. CD56 lymphoproliferative disorders of the skin: A multicenter study of the cutaneous lymphoma project group of the european organization for research and greatment of cancer (EORTC). J Clin Pathol. 60(9): 981-9. (IHC frozen PubMed)

Xu. W., B. He, et al. 2007. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLP1. Nature Immunol. 8(3): 294-303. (IHC frozen PubMed)

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