Anti-Human CD123 eFluor® 650NC

Also known as: Interleukin-3 Receptor alpha, IL-3Ra

Clone: 6H6

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 95-1239

Cat. No.	Size
95-1239-41	25 tests
95-1239-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells with Anti-Human CD85g (ILT7) PE (cat. 12-5179) and...View More

Description

Description: The 6H6 monoclonal antibody reacts with human CD123, the \alpha chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common beta chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	eFluor 650NC
Laser	Violet Laser
Emit	650 nm
Excite	350 - 635 nm
Legal	Under patent number: US 7,939,170 and additional pending patent application(s)
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
14-1239	Anti-Human CD123 Purified			FC, IHC	RUO
45-1239	Anti-Human CD123 PerCP-Cyanine5.5	488 nm		FC	RUO
12-1239	Anti-Human CD123 PE	488 - 561 nm		FC	RUO
48-1239	Anti-Human CD123 eFluor® 450	405 nm	450 nm	FC	RUO
15-1239	Anti-Human CD123 PE-Cyanine5	488 - 561 nm		FC	RUO
25-1239	Anti-Human CD123 PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO
13-1239	Anti-Human CD123 Biotin			FC	RUO
11-1239	Anti-Human CD123 FITC	488 nm		FC	RUO
17-1239	Anti-Human CD123 APC	633 - 647 nm	660 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
00-4222	Flow Cytometry Staining Buffer			FC	GPR
12-5179	Anti-Human CD85g (ILT7) PE	488 - 561 nm	575 nm	FC	RUO
45-5179	Anti-Human CD85g (ILT7) PerCP-Cyanine5.5	488 nm		FC	RUO
48-9952	Anti-Human HLA-DR eFluor® 450	405 nm	450 nm	FC	RUO
95-4714	Mouse IgG1 K Isotype Control eFluor® 650NC	350 - 635 nm	650 nm	FC	RUO

References

References: Herling, M., M. Teitell, R. Shen, L. Medeiros, and D. Jones. 2003. TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood. 101: 5007-5009.

Jaye, D.L., C.M. Geigerman, et al. 2006. Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+CD56+ hematodermic neoplasms. Mod Pathol. 19(12): 1555-62. (IHC paraffin PubMed)

Peduzzi, E., C. Groeper, et al. 2007. Local activation of the innate immune system in Buruli Ulcer lesions. J Invest Dermatol. 127(3) :638-45. (IHC paraffin PubMed)

Assaf C., S. Gellrich, et al. 2007. CD56 lymphoproliferative disorders of the skin: A multicenter study of the cutaneous lymphoma project group of the european organization for research and greatment of cancer (EORTC). J Clin Pathol. 60(9): 981-9. (IHC frozen PubMed)

Xu. W., B. He, et al. 2007. Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLP1. Nature Immunol. 8(3): 294-303. (IHC frozen PubMed)

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD123	Stem Cell Biology Cell Signaling Cytokines, Chemokines, Growth Factors	B Cells Dendritic Cells	eFluor 650NC