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Anti-Human CD11a Functional Grade Purified

Also known as: Integrin alpha L, ITGAL, Lymphocyte Function-Associated Antigen, Type 1 alpha (LFA-1 alpha), LFA1A

Clone: HI111

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 16-0119

Cat. No. Size
16-0119-81 50 ug
16-0119-85 500 ug
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Data for Anti-Human CD11a Functional Grade Purified.

Staining of normal human peripheral blood with Anti-Human CD11a Functional Grade Purified and...View More

  • Data for Anti-Human CD11a Functional Grade Purified.
Description

Description: The HI111 monoclonal antibody reacts with human CD11a, the 180 kDa integrin αL, also known as the lymphocyte function associated antigen-1 (LFA-1) α chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin β2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.

Details
Host Mouse
Isotype IgG1, kappa
Reactivity Human
Reported Applications Flow Cytometric Analysis, Functional Assays
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
14-0119 Anti-Human CD11a Purified FC, IHC, FA RUO
11-0119 Anti-Human CD11a FITC 488 nm 518 nm FC RUO
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References

References: Kapsogeorgou EK, Dimitriou ID, Abu-Helu RF, Moutsopoulos HM, Manoussakis MN. Activation of epithelial and myoepithelial cells in the salivary glands of patients with Sjögren's syndrome: high expression of intercellular adhesion molecule-1 (ICAM.1) in biopsy specimens and cultured cells. Clin Exp Immunol. 2001 Apr;124(1):126-33. (HI111, IHC frozen)

Knapp, W., B. Dorken, et al. eds 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.

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