Anti-Human CD117 (c-Kit) PE-Cyanine7

Also known as: SCFR, Steel Factor Receptor

Clone: 104D2

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-1178

Cat. No.	Size
25-1178-41	25 tests
25-1178-42	100 tests
Please inquire about custom configurations or bulk packaging.

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Staining of normal human peripheral blood cells with the Human Hematopoietic Lineage APC Cocktail...View More

Description

Description: The 104D2 monoclonal antibody reacts with human CD117, also known as c-Kit , Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145 kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	775 nm
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
48-1178	Anti-Human CD117 (c-Kit) eFluor® 450	405 nm		FC	RUO
11-1178	Anti-Human CD117 (c-Kit) FITC	488 nm		FC	RUO
46-1178	Anti-Human CD117 (c-Kit) PerCP-eFluor® 710	488 nm	710 nm	FC	RUO
12-1178	Anti-Human CD117 (c-Kit) PE	488 - 561 nm		FC	RUO
17-1178	Anti-Human CD117 (c-Kit) APC	633 - 647 nm	660 nm	FC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
11-0349	Anti-Human CD34 FITC	488 nm	518 nm	FC	RUO
22-7776	Human Hematopoietic Lineage APC Cocktail			FC	RUO
25-4714	Mouse IgG1 K Isotype Control PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO

References

References: Blair A, Sutherland HJ. Primitive acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo lack surface expression of c-kit (CD117). Exp Hematol. 2000 Jun;28(6):660-71.

Schlossman, S., L. Bloumsell, et al. eds. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York 1995. (104D2, FC)

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD117 (c-kit)	Stem Cell Biology Cell Signaling Angiogenesis	Hematopoietic Stem Cells	PE-Cyanine7