Anti-Human CD103 (Integrin alpha E) PE-Cyanine7

Also known as: Integrin aE, ITGAE

Clone: B-Ly7

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 25-1038

Cat. No.	Size
25-1038-41	25 tests
25-1038-42	100 tests
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Staining of 3-day PHA-stimulated human peripheral blood cells with Mouse IgG1 K Isotype Control...View More

Description

Description: The B-Ly7 monoclonal antibody reacts with human CD103, the alpha E integrin. CD103 non-covalently associates with integrin beta 7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen, E-cadherin, binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cyanine7
Laser	Blue Laser, Green Laser, Yellow-Green Laser
Emit	775 nm
Excite	488 - 561 nm
Legal	FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT FOR NON-COMMERCIAL RESEARCH USE ONLY. NOT FOR THERAPEUTIC OR IN VIVO APPLICATIONS. OTHER USE NEEDS LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. UNDER U.S. PATENT # 5,268,486, 5,569,587 AND 5,627,027 AND FOREIGN EQUIVALENTS AND PENDING APPLICATIONS. THIS MATERIAL IS SUBJECT TO PROPRIETARY RIGHTS OF GE HEALTHCARE BIO-SCIENCES CORP. AND CARNEGIE MELLON UNIVERSITY AND MADE AND SOLD UNDER LICENSE FROM GE HEALTHCARE BIO-SCIENCES CORP. THIS PRODUCT IS LICENSED FOR SALE ONLY FOR RESEARCH. IT IS NOT LICENSED FOR ANY OTHER USE. THERE IS NO IMPLIED LICENSE HEREUNDER FOR ANY COMMERCIAL USE. COMMERCIAL USE shall include: 1. sale, lease, license or other transfer of the material or any material derived or produced from it; 2. sale, lease, license or other grant of rights to use this Material or any material derived or produced from it; 3. use of this material to perform services for a fee for third parties. IF YOU REQUIRE A COMMERCIAL LICENSE TO USE THIS MATERIAL AND DO NOT HAVE ONE, RETURN THIS MATERIAL, UNOPENED TO EBIOSCIENCE, INC. 10255 SCIENCE CENTER DRIVE, SAN DIEGO, CALIFORNIA 92121 USA AND ANY MONEY PAID FOR THE MATERIAL WILL BE REFUNDED.
Reported Applications	Flow Cytometric Analysis

Documentation

TDS Link	Download TDS

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
11-1038	Anti-Human CD103 (Integrin alpha E) FITC	488 nm	518 nm	FC	RUO
17-1038	Anti-Human CD103 (Integrin alpha E) APC	633 - 647 nm	660 nm	FC	RUO
12-1038	Anti-Human CD103 (Integrin alpha E) PE	488 - 561 nm	575 nm	FC	RUO
14-1038	Anti-Human CD103 (Integrin alpha E) Purified			FC, IHC	RUO

Related Products

Cat. No.	Name	Excite	Emit	Application	Reg.
25-4714	Mouse IgG1 K Isotype Control PE-Cyanine7	488 - 561 nm	775 nm	FC	RUO

References

References: de Harven E, Soligo D, Christensen H. 1995. Immunogold labeling for the diagnosis of leukemia by transmission and scanning electron microscopy. Scanning Microsc. 9:1191-199

de Harven E, Christensen H, Poppema S, Scott JG. 1994. Immunogold labelling of leukemic hairy cells with the B-ly7 monoclonal antibody: an SEM and TEM study. Microsc Res Tech. 28:356-67

Visser L, Dabbagh L, Poppema S. 1992. Reactivity of monoclonal antibody B-ly7 with a subset of activated T cells and T-cell lymphomas. Hematol Pathol. 6:37-42

Thaler J, Dietze O, Faber V, Greil R, Gastl G, Denz H, Ho AD, Huber H. 1990. Monoclonal antibody B-ly7: a sensitive marker for detection of minimal residual disease in hairy cell leukemia. Leukemia. 4:170-6

Schwarting R, Dienemann D, Kruschwitz M, Fritsche G, Stein H. 1990. Specificities of monoclonal antibodies B-ly7 and HML-1 are identical. Blood. 75:320-1

View More Products

Antigens	Area of Biology	Cell Type	Formats
CD103 (Integrin alpha E)	Adaptive Immunity Adhesion & Migration Angiogenesis	Dendritic Cells T Cells Treg Cells	PE-Cyanine7