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Anti-Human CD103 (Integrin alpha E) APC

Also known as: Integrin aE, ITGAE

Clone: Ber-ACT8

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# 17-1037

Cat. No. Size
17-1037-41 25 tests
17-1037-42 100 tests
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Data for Anti-Human CD103 (Integrin alpha E) APC.

Staining of 3-day PHA-stimulated normal human peripheral blood cells with Anti-Human CD8a...View More

  • Data for Anti-Human CD103 (Integrin alpha E) APC.
Description

Description: The Ber-ACT8 monoclonal antibody reacts with human CD103, the alphaE integrin. CD103 non-covalently associates with integrin beta7. CD103 is expressed mainly on intraepithelial lymphocytes and a small subset of peripheral lymphocytes. CD103 is also expressed by hairy cell leukemia (HCL) and by some chronic B cell lymphocytic leukemias. \I{In vitro\I} stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen (E-cadherin) binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. Cross-blocking studies suggest that antibody clones B-Ly7 and Ber-ACT8 see different epitopes.

Details
Host Mouse
Isotype IgG1
Reactivity Human
Conjugate APC
Laser Red Laser
Emit 660 nm
Excite 633 - 647 nm
Reported Applications Flow Cytometric Analysis
Documentation
TDS Link Download TDS
Additional Formats
Cat. No. Name Excite Emit Application Reg.
11-1037 Anti-Human CD103 (Integrin alpha E) FITC 488 nm 518 nm FC RUO
12-1037 Anti-Human CD103 (Integrin alpha E) PE 488 - 561 nm 575 nm FC RUO
46-1037 Anti-Human CD103 (Integrin alpha E) PerCP-eFluor® 710 488 nm 710 nm FC RUO
Related Products
Cat. No. Name Excite Emit Application Reg.
17-4714 Mouse IgG1 K Isotype Control APC 633 - 647 nm 660 nm FC RUO
46-0087 Anti-Human CD8a PerCP-eFluor® 710 488 nm 710 nm FC RUO
References

References: Cepek KL, Wong DA, Brenner MB, Springer TA. 1995. CD103 cluster reort. Leucocyte Typing V. 1995.

Kruschwitz M, Frtizsche G, Schwarting R, Micklem K, Mason DY, Falini B, Stein H. 1995. Ber-ACT8: new monoclonal antibody to the mucosa lymphocyte antigen. J Clin Pathol 1991; 44(8):636-45. (Ber-ACT8, PubMed)

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