CD10 PE-Cy7

Clone: SN5c

CE

SKU# 9025-0108

Cat. No.	Size
9025-0108-025	25 tests
9025-0108-120	120 tests
Please inquire about custom configurations or bulk packaging.

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Fluorescence profiles of normal human peripheral blood granulocytes unstained (blue histogram) or...View More

Description

Description: The SN5c monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein. CD10 was shown to be the same molecule as neutral endopeptidase (NEP), or KII-NA. CD10 is a zinc-dependent metallopeptidase acting on substrates such as endothelin, glucagon, gastrin, neurotensin and bradykinin. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and its expression has been reported on mature germinal center B cells. CD10 expression is also found on normal donor granulocytes and bone marrow stromal cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PE-Cy7
Laser	Blue Laser
Emit	760 nm
Excite	488 nm
Legal	For research (not to include in vivo research) and/or in vitro diagnostic use only. The only permitted commercial use is provision of research (not to include in vivo research) services and/or in vitro diagnostic services. Not for therapeutic or in vivo applications. Other use needs licenses which are available from GE Healthcare Bio-Sciences Corp. Under U.S. patent nos. Nos 5,268,486, 5,569,587 and 5,627,027 and foreign equivalents and pending applications. This product is subject to proprietary rights of GE Healthcare Bio-Sciences Corp. (“GE Healthcare”) and Carnegie Mellon University (“CMU”) and made and sold under license from GE Healthcare. The product bearing this label is licensed for sale only for research (not to include in vivo research) and in addition may be used to perform research (not to include in vivo research) and/or in vitro diagnostic services for third parties. It is not licensed nor are there any implied licenses for any other use including, without limitation, commercial uses unless expressly authorized by GE Healthcare in writing. If you intend to use this product commercially and you do not have a license to use this product for the intended commercial purpose, return this product, unopened to eBioscience, Inc. 10255 Science Center Drive, San Diego, California 92121 USA and any money paid for the product will be refunded.
Reported Applications	Flow Cytometric Analysis

Documentation

For complete product information, please download the TDS or IFU document.

Instructions for Use (English)	Download English IFU
Instructions for Use (French)	Download French IFU
Instructions for Use (German)	Download German IFU
Instructions for Use (Italian)	Download Italian IFU
Instructions for Use (Spanish)	Download Spanish IFU

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
9011-0108	CD10 FITC	488 nm	518 nm	FC	CE
9017-0108	CD10 APC	633 - 647 nm	660 nm	FC	CE
9012-0108	CD10 PE	488 nm	575 nm	FC	CE
9047-0108	CD10 APC-eFluor® 780	633 - 647 nm	780 nm	FC	CE

References

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Kishimoto T, von dem Borne AE, et al, eds. Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing Inc. London. 1998.

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