Human C-reactive Protein Instant ELISA

Also known as: C reactive protein, pentraxin related, PTX1

RUO: For Research Use Only. Not for use in diagnostic procedures.

SKU# BMS288INST*

Cat. No. Size
BMS288INST 128 tests
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Data for Human C-reactive Protein Instant ELISA.

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  • Data for Human C-reactive Protein Instant ELISA.
Description

Description: The human C-reactive protein Instant ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human C-reactive protein. The human C-reactive protein Instant ELISA is for research use only. Not for diagnostic or therapeutic procedures.

C-reactive protein is an acute phase protein exclusively synthesized by hepatocytes in response to cytokines released into circulation by activated leukocytes. Serum and plasma levels of CRP have been shown to rise during response to a wide variety of diseases including bacterial infections, acute phase of rheumatoid arthritis, inflammation of the bile duct. High CRP is also found in Guillain-Barre syndrome patients, in multiple sclerosis, viral infections, tuberculosis, acute infectious hepatitis, necrotic diseases, burned patients and after surgical trauma.

CRP thus has been shown to be a useful indicator of inflammatory processes. CRP levels rise in serum or plasma within 24 to 48 hours after acute tissue damage, peaking at acute stage and decreasing with resolution of inflammation or trauma. In addition to being a marker of inflammatory diseases, CRP turned out to be a predictive value as cardiac marker to assess risk of cardio vascular and peripheral vascular disease.

Details
Reactivity Human
Sample Volume 100 uL (1:500 prediluted)
Suitable Sample Types cell culture supernatant, serum, plasma (EDTA, citrate, heparin)
Sensitivity 3.0 pg/mL
Standard Curve Range 78 - 5,000 pg/mL
Components Aluminium pouch(es) with a Microwell Plate coated with Polyclonal Antibody (murine) to human C-reactive protein, HRP-Conjugate (anti human C-reactive protein monoclonal (murine) antibody) and Assay Buffer, lyophilized
Aluminium pouch(es) with a human C-reactive protein Standard curve (coloured)
Wash Buffer Concentrate 20x (phosphate-buffered saline with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Stop Solution (1M Phosphoric acid)
Adhesive Plate Covers
Reported Applications ELISA
Documentation
TDS Link Download TDS
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References

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Ceriello,Antonio; Assaloni,Roberta; Da Ros,Roberto; Maier,Amabile; Piconi,Ludovica; Quagliaro,Lisa; Esposito,Katherine; Giugliano,Dario. Effect of Atorvastatin and Irbesartan, Alone and in Combination, on Postprandial Endothelial Dysfunction, Oxidative Stress, and Inflammation in Type 2 Diabetic Patients. Circulation 2005;111:2518-2524. (Link)

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