Citations: Gajate,Consuelo; Mollinedo,Faustino. Cytoskeleton-mediated Death Receptor and Ligand Concentration in Lipid Rafts Forms Apoptosis-promoting Clusters in Cancer Chemotherapy. Journal of Biological Chemistry 2005;280:11641-11647. (Link)
Scotlandi,Katia; Baldini,Nicola; Cerisano,Vanessa; Manara,Maria Cristina; Benini,Stefania; Serra,Massimo; Lollini,Pier Luigi; Nanni,Patrizia; Nicoletti,Giordano; Bernard,Ghislaine; Bernard,Alain; Picci,Piero. CD99 Engagement: An Effective Therapeutic Strategy for Ewing Tumors. Cancer Research 2000;60:5134-5142. (Link)
Cabaner,Christelle; Gajate,Consuelo; Macho,Antonio; Munoz,Eduardo; Modolell,Manuel; Mollinedo,Faustino. Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: Involvement of the Fas receptor/ligand system. British Journal of Pharmacology 1999;127:813-825. (Link)
Mcgahon,Anne J.; Costa Pereira,Ana P.; Daly,Lisa; Cotter,Thomas G.. Chemotherapeutic drug-induced apoptosis in human leukaemic cells is independent of the Fas (APO-1/CD95) receptor/ligand system. British Journal of Haematology 1998;101:539-547. (Link)
Gajate,Consuelo; Mollinedo,Faustino. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts. Blood 2006;109:blood-2006. (Link)
Gajate,Consuelo; Canto-Janez,Esther; Acuna,A.Ulises; Amat-Guerri,Francisco; Geijo,Emilio; Santos-Beneit,Antonio M.; Veldman,Robert J.; Mollinedo,Faustino. Intracellular Triggering of Fas Aggregation and Recruitment of Apoptotic Molecules into Fas-enriched Rafts in Selective Tumor Cell Apoptosis. Journal of Experimental Medicine 2004;200:353-365. (Link)
Fumarola C,A Zerbini and G G Guidotti. Glutamine deprivation-mediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis. Cell Death and Differentiation 2001;8:1004-1013. (Link)
Maeda,Hiroshi; Hori,Seiji; Nishitoh,Hideki; Ichijo,Hidenori; Ogawa,Osamu; Kakehi,Yoshiyuki; Kakizuka,Akira. Tumor Growth Inhibition by Arsenic Trioxide (As2O3) in the Orthotopic Metastasis Model of Androgen-independent Prostate Cancer. Cancer Research 2001;61:5432-5440. (Link)
Gajate,Consuelo; Mollinedo,Faustino. The antitumor ether lipid ET-18-OCH3 induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells. Blood 2001;98:3860-3863. (Link)
O'Gorman,D.M.; McKenna,S.L.; McGahon,A.J.; Cotter,T.G.. Inhibition of PI3-kinase sensitises HL60 human leukaemia cells to both chemotherapeutic drug- and Fas-induced apoptosis... Leukemia Research 2001;25:801-811. (Link)
Sciorati,Clara; Rovere,Patrizia; Ferrarini,Marina; Paolucci,Clara; Heltai,Silvia; Vaiani,Roberto; Clementi,Emilio; Manfredi,Angelo A.. Generation of Nitric Oxide by the Inducible Nitric Oxide Synthase Protects {gamma}{delta} T Cells from Mycobacterium tuberculosis-Induced Apoptosis. The Journal of Immunology 1999;163:1570-1576. (Link)
Mahajan,Sandeep; Ghosh,Sutapa; Sudbeck,Elise A.; Zheng,Yaguo; Downs,Suzanne; Hupke,Michael; Uckun,Fatih M.. Rational Design and Synthesis of a Novel Anti-leukemic Agent Targeting Bruton's Tyrosine Kinase (BTK), LFM-A13 [alpha -Cyano-beta -Hydroxy-beta -Methyl-N-(2,5-Dibromophenyl)Propenamide]. Journal of Biological Chemistry 1999;274:9587-9599. (Link)
Vassilev,Alexei; Ozer,Zahide; Navara,Christopher; Mahajan,Sandeep; Uckun,Fatih M.. Bruton's Tyrosine Kinase as an Inhibitor of the Fas/CD95 Death-inducing Signaling Complex. Journal of Biological Chemistry 1999;274:1646-1656. (Link)
Nieto-Miguel,Teresa; Gajate,Consuelo; Mollinedo,Faustino. Differential Targets and Subcellular Localization of Antitumor Alkyl-lysophospholipid in Leukemic Versus Solid Tumor Cells. Journal of Biological Chemistry 2006;281:14833-14840. (Link)
Gajate,Consuelo; Gonzalez-Camacho,Fernando; Mollinedo,Faustino. Involvement of Raft Aggregates Enriched in Fas/CD95 Death-Inducing Signaling Complex in the Antileukemic Action of Edelfosine in Jurkat Cells. PLoS ONE 2009;4:(Link)
Wood,Carla M.; Goodman,Patricia A.; Vassilev,Alexei O.; Uckun,Fatih M.. CD95 (APO-1/FAS) deficiency in infant acute lymphoblastic leukemia: detection of novel soluble Fas splice variants. European Journal of Haematology 2003;70:156-171. (Link)
