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Human CD Chart
Human non-CD Chart
Table 1: Human CD Cellular Antigens
|
Human CD Cellular Antigens
|
| Antigen Name |
Other Names |
MW |
Structure |
Distribution |
Function |
eBioscience Clone |
Formats |
| CD1a
|
T6
|
49kD
|
IgSF, MHC-like
|
cortical thymocytes, Langerhans cells, DC
|
antigen presentation, w/ β2m
|
HI149
|
PU, B, F, PE, Alexa FluorŽ 488, Alexa FluorŽ 647, Pacific BlueŽ
|
| CD1b
|
T6
|
45kD
|
IgSF, MHC-like
|
cortical thymocytes, Langerhans cells, DC
|
antigen presentation, w/ β2m
|
eBioSN13
|
PU, B
|
| CD1c
|
T6
|
43kD
|
IgSF, MHC-like
|
cortical thymocytes, Langerhans cells, DC, B subset
|
antigen presentation, w/ β2m
|
|
|
| CD1d
|
|
49kD
|
IgSF, MHC-like
|
intestinal epith, B subset, monolow, DC
|
antigen presentation, w/ β2m
|
|
|
| CD1e
|
|
28kD
|
IgSF, MHC-like
|
DC
|
antigen presentation, w/ β2m
|
|
|
| CD2
|
T11, LFA-2, SRBC-R
|
50kD
|
IgSF
|
thymocytes, T, NK
|
CD58 ligand, adhesion, T cell activation
|
RPA-2.10
|
PU, FG, B, F, PE, PE-Cy5
|
| CD2R
|
T11-3
|
50kD
|
IgSF
|
Tact
|
activation-dependent form of CD2
|
|
|
| CD3γ, CD3δ
|
T3
|
|
IgSF
|
T, thymocyte subset
|
w/ TCR, TCR surface expression/signal transduction
|
|
|
| CD3ε
|
T3
|
20kD
|
IgSF
|
T, thymocyte subset
|
w/ TCR, TCR surface expression/signal transduction
|
OKT3
|
PU, FG, F, PE, Alexa FluorŽ 488, Alexa FluorŽ 647, Pacific BlueŽ
|
|
|
|
|
|
|
|
UCHT1
|
PU, FG, B, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem
|
|
|
|
|
|
|
|
HIT3a
|
PU, FG, F, PE
|
| CD4
|
T4
|
55kD
|
IgSF
|
thymocyte subset, T subset, mono, mac
|
MHC class II coreceptor, HIV receptor,
T cell differentiation/activation
|
RPA-T4
|
PU, FG, B, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem
|
|
|
|
|
|
|
|
OKT4
|
PU, FG, B, F, PE, PE-Cy5.5, APC, Alexa FluorŽ 488, Alexa FluorŽ 647, Alexa FluorŽ 700, Pacific BlueŽ
|
| CD5
|
T1, Tp67
|
67kD
|
Scavenger R SF
|
thymocytes, T, B subset, B-CLL
|
CD72 receptor, TCR or BCR
signaling, T-B interaction
|
UCHT2
|
PU, B, F, PE,
PE-Cy7
|
| CD6
|
T12
|
100-130kD
|
Scavenger R SF
|
thymocytes, T, B subset
|
CD166 receptor,
T cell differentiation/
costimulation
|
|
|
| CD7
|
|
40kD
|
IgSF
|
hematopoietic progenitors,
thymocytes, T, NK
|
T costimulation
|
CD7-6B7
|
PU, B, F, PE,
PE-Cy5, APC
|
| CD8a
|
T8, Leu-2
|
32-34kD
|
IgSF
|
thymocyte subset, T subset, NK
|
MHC class I coreceptor, receptor for some
mutated HIV-1, T cell differentiation/activation
|
RPA-T8
|
PU, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem
|
|
|
|
|
|
|
|
HIT8a
|
PU, FG, B, F, PE
|
|
|
|
|
|
|
|
OKT8
|
PU, FG, B, F, PE, APC, Alexa FluorŽ 488, Alexa FluorŽ 647, Alexa FluorŽ 700, Pacific BlueŽ
|
| CD8b
|
|
30-32kD
|
IgSF
|
thymocyte subset, T subset
|
|
|
|
| CD9
|
p24, MRP-1
|
22-27kD
|
TM4SF
|
pre-B, eosinophils, basophils, platelets, Tact
|
cellular adhesion and migration
|
eBioSN4 (SN4 C3-3A2)
|
PU, B, F, PE
|
| CD10
|
CALLA, NEP, gp100
|
100kD
|
type II TM
|
B precursors, T precursors, neutrophils
|
zinc-binding metalloproteinase, B cell development
|
eBioCB-CALLA (CB-CALLA)
|
PU, B, F, PE, PE-Cy5, APC
|
| CD11a
|
LFA-1, integrin αL
|
180kD
|
Integrin family
|
lymph, gran, mono, mac
|
CD11a/CD18 receptor for ICAM-1, -2,-3, intercellular
adhesion, T costimulation
|
HI111
|
PU, FG, F, PE
|
| CD11b
|
Mac-1, integrin αM
|
170kD
|
Integrin family
|
myeloid cells, NK
|
binds CD54, ECM, iC3b
|
CBRM1/5
|
PU, FG, F, PE, Alexa FluorŽ 647, Alexa FluorŽ 700
|
|
|
|
|
|
|
|
ICRF44
|
PU, B, PE, PE-Cy7
|
| CD11c
|
p150, 95, CR4, integrin αX
|
150kD
|
Integrin family
|
DC, myeloid cells, NK, B, T subset
|
binds CD54, fibrinogen and iC3b
|
3.9
|
PU, B, F, PE, PE-Cy7, APC
|
| CDw12
|
|
90-120kD
|
|
mono, gran, platelets
|
|
|
|
| CD13
|
Aminopeptidase N, APN
|
150-170kD
|
type II TM
|
myeloid cells
|
zinc-binding metalloproteinase, antigen processing,
receptor for corona virus strains
|
WM-15
|
PU, FG, F, PE, APC
|
| CD14
|
LPS-R
|
53-55kD
|
GPI-linked
|
mono, mac, Langerhans cells, granlow
|
receptor for LPS/LBP, LPS recognition
|
61D3
|
PU, FG, B, F, PE, PE-Cy7, APC
|
| CD15
|
Lewis-x, Lex
|
|
CHO
|
neutrophils, eosinophils, mono
|
adhesion
|
HI98
|
PU, B, F
|
| CD15s
|
Sialyl Lewis X
|
|
CHO
|
neutrophils, eosinophils, mono, memory helper T, Tact
and B, NK, HEV
|
CD62L and CD62P ligand, adhesion
|
|
|
| CD15u
|
Sulfated Lewis X
|
|
CHO
|
myeloid subset
|
adhesion
|
|
|
| CD16a
|
FcγRIIIA
|
50-65kD
|
IgSF
|
neutrophils, mac, NK
|
component of low affinity Fc receptor, phagocytosis
and ADCC
|
eBioCB16 (CB16)
|
PU, FG, B, PE
|
| CD16b
|
FcγRIIIB
|
48kD
|
IgSF
|
neutrophils
|
component of low affinity Fc receptor, phagocytosis
and ADCC
|
|
|
| CDw17
|
|
|
|
neutrophils, mono, platelets
|
lactosyl ceramide
|
|
|
| CD18
|
Integrin β2
|
95kD
|
Integrin family
|
broad, all leukocytes
|
w/ CD11a, b & c, adhesion
|
CLB-LFA-1/1
|
PU, F, PE
|
| CD19
|
B4
|
95kD
|
IgSF
|
B, FDC
|
complex w/ CD21and CD81, BCR coreceptor, B cell
activation/ differentiation
|
HIB19
|
PU, FG, B, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem, Alexa FluorŽ 488, Alexa FluorŽ 647, Alexa FluorŽ 700, Pacific BlueŽ
|
| CD20
|
B1, Bp35
|
33-37kD
|
TM4SF
|
B, T subset
|
B cell activation
|
2H7
|
PU, B, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem, Alexa FluorŽ 488, Alexa FluorŽ 647, Alexa FluorŽ 700, Pacific BlueŽ
|
| CD21
|
C3DR, CR2, EBV-R
|
145,110kD
|
CCRSF
|
B, FDC, T subset
|
complement C3d and EBV receptor, complex w/ CD19
and CD81, BCR coreceptor
|
BU32
|
PE, PE-Cy5
|
| CD22
|
BL-CAM, Siglec-2
|
150kD
|
IgSF, sialoadhesins
|
B
|
adhesion, B-mono, B-T interactions
|
|
|
| CD23
|
FcεRII
|
45kD
|
C-type lectin
|
B, activated mac, eosinophils, FDC, platelets
|
CD19-CD21-CD81 receptor, IgE low affinity receptor,
signal transduction
|
EBVCS2
|
PU, F, PE, PE-Cy7, APC
|
| CD24
|
BA-1
|
35-45kD
|
GPI-linked
|
thymocytes, erythrocytes, peripheral lymph, myeloid
|
binds P-selectin
|
eBioSN3 (SN3 A5-2H10)
|
PU, B, F, PE
|
| CD25
|
Tac, p55
|
55kD
|
type I TM
|
Tact, Bact, lymph progenitors
|
IL-2Rα, w/ IL-2Rβ and γ to form high affinity complex
|
BC96
|
PU, B, F, PE, PE-Cy5, PE-Cy7, APC
|
| CD26
|
DPP IV
|
110kD
|
type II TM
|
thymocyte subset, Tact, soluble form
|
dipeptidyl peptidase, T costimulation, HIV entry
|
2A6
|
PU, F, PE
|
| CD27
|
T14
|
50-55kD
|
TNFRSF
|
medullary thymocytes, T, B subset, NK subset
|
CD70 receptor, T costimulation
|
O323
|
PU, B, F, PE, APC, APC-Tandem, Alexa FluorŽ 700
|
|
|
|
|
|
|
|
LG.7F9
|
PU, FG, B, F, PE, APC
|
| CD28
|
Tp44, T44
|
44kD
|
IgSF
|
most T, thymocytes, plasma cells
|
CD80, CD86 receptor, T costimulation
|
CD28.2
|
PU, FG, B, F, PE, PE-Cy7, APC
|
|
|
|
|
|
|
|
CD28.6
|
FG
|
| CD29
|
Integrin β1
|
130kD
|
Integrin family
|
lymph, mono, granlow, platelets, mast cells, fibroblasts,
endoth
|
w/ CD49a (VLA-1) receptor for VCAM-1, MAdCAM-1
and ECM
|
MEM-101A
|
PU, F, PE, PE-Cy5
|
| CD30
|
Ki-1
|
105-120kD
|
TNFRSF
|
Bact, T and NK , Reed-Sternberg cells, anaplastic large
cell lymphoma
|
CD153 receptor, lymph proliferation/ apoptosis
|
|
|
| CD31
|
PECAM-1
|
130-140kD
|
IgSF
|
mono, platelets, gran, endoth, lymph subset
|
CD38 receptor, adhesion
|
WM59
|
PU, FG, B, F, PE, APC
|
| CD32
|
FcγRII
|
40kD
|
IgSF
|
mono, gran, B, platelets
|
low affinity Fc receptor for aggregated Ig and immune
complexes
|
|
|
| CD33
|
p67, Siglec-3
|
67kD
|
IgSF, sialoadhesins
|
myeloid progenitors, mono, gran, DC, mast cells, Tact
|
adhesion
|
HIM3-4
|
PU, F, PE, PE-Cy5
|
|
|
|
|
|
|
|
WM53
|
PU, F, PE, PE-Cy5, PE-Cy7, Alexa FluorŽ 700
|
| CD34
|
|
105-120kD
|
Sialomucin, type I TM
|
hematopoietic precursors, capillary endoth,
embryonic fibroblasts
|
stem cell marker, adhesion, CD62L receptor
|
|
|
| CD35
|
CR1
|
250kD
|
CCRSF
|
erythrocytes, B, mono, neutrophils, eosinophils,
FDC, T subset
|
complement receptor 1, binds C3b and C4b,
adhesion, phagocytosis
|
|
|
| CD36
|
GPIV
|
88kD
|
|
platelets, mono, mac, endoth, early erythrocytes
|
ECM receptor, adhesion, phagocytosis
|
mAb (please inquire)
|
PU
|
| CD37
|
|
40-52kD
|
TM4SF
|
B, Tlow, granlow
|
signal transduction
|
|
|
| CD38
|
T10
|
45kD
|
|
variable levels on majority of
hematopoietic cells, high expression
on plasma cells, B and Tact
|
ecto-ADP-ribosyl cyclase,
cell activation
|
HIT2
|
PU, B, F, PE, PE-Cy5,
PE-Cy7, APC, APC-Cy5.5
|
| CD39
|
|
78kD
|
NK, mac, Langerhans
cells, DC, Bact
|
B cell adhesion,
protects activated cells
from lysis, ecto-apyrase
|
|
|
|
| CD40
|
|
48kD
|
TNFRSF
|
B, mono, mac, FDC,
endoth, T subset
|
CD154 receptor, B
differentiation/ costimulation,
isotype-switching, rescues B
cells from apoptosis
|
5C3
|
PU, FG, F, PE
|
| CD41
|
gpIIb
|
125/22kD
|
Integrin family
|
platelets, megakaryocytes
|
w/ CD61 forms GPIIb, binds fibrinogen,
fibronectin, vWF, thrombospondin, platelet activation
and aggregation
|
HIP2
|
PU, F
|
|
|
|
|
|
|
|
HIP8
|
PU, F, PE
|
| CD42a
|
GPIX
|
22kD
|
LRRF
|
platelets, megakaryocytes
|
complex w/ CD42b, c and d, receptor for vWF and
thrombin, platelet adhesion to subendothelial matrices
|
|
|
| CD42b
|
GPIba
|
145kD
|
LRRF
|
platelets, megakaryocytes
|
complex w/ CD42a, c and d, binds to vWF and
thrombin, platelet adhesion/ activation
|
HIP1
|
PU, FG, F, PE
|
| CD42c
|
GPIbb
|
24kD
|
LRRF
|
platelets, megakaryocytes
|
complex w/ CD42a, b, d
|
|
|
| CD42d
|
GPV
|
82kD
|
LRRF
|
platelets, megakaryocytes
|
complex w/ CD42a-c
|
|
|
| CD43
|
Leukosialin, sialophorin
|
115-135kD
|
Sialomucin,
type I TM
|
leukocytes, except resting B, plateletslow
|
inhibition of T cell interaction, CD54R, adhesion
|
L10
|
PU, F, PE, APC
|
| CD44
|
H-CAM, Pgp-1
|
80-95kD
|
hyaladherin family
|
hematopoietic and non-hematopoietic cells, except
platelets, hepatocytes, testis
|
binds hyaluronic acid, adhesion
|
IM7
|
PU, FG, B, F, PE, PE-Cy5, PE-Cy5.5, PE-Cy7,
APC, APC-Tandem, Alexa FluorŽ 700, Pacific BlueŽ
|
| CD44R
|
CD44v
|
|
|
CD44 variants heterogeneous expression,
constitutively on epith, mono, upregulated on activated
leukocytes
|
adhesion, metastasis
|
|
|
| CD45
|
LCA, T200, B220
|
180-240kD
|
|
hematopoietic cells, multiple isoforms from alternative
splicing
|
tyrosine phosphatase, enhanced TCR & BCR signals
|
HI30
|
PU, B, F, PE, PE-Cy5, PE-Cy5.5, PE-Cy7, APC,
APC-Tandem, Cy5
|
|
|
|
|
|
|
|
RA3-6B2
|
PU, FG, B, F, PE, PE-Cy5, PE-Cy5.5, PE-Cy7, APC, APC-Cy5.5, APC-Tandem, Cy5, Alexa FluorŽ 488, Alexa FluorŽ 647, Pacific BlueŽ
|
| CD45RA
|
|
205-220kD
|
|
B, T subset(naive), mono
|
exon A isoforms of CD45
|
HI100
|
PU, B, F, PE, PE-Cy5, APC, Pacific BlueŽ
|
|
|
|
|
|
|
|
JS-83
|
PU, B, F, PE, PE-Cy5
|
| CD45RB
|
|
190-220kD
|
|
T subset, B, mono, mac, gran
|
exon B isoforms of CD45
|
MEM-55
|
PU, F, PE, PE-Cy5
|
| CD45RO
|
|
180kD
|
|
Tact, memory T, B subset, mono, mac, gran
|
isoform of CD45 lacking A, B, C exons
|
UCHL1
|
PU, F, PE, PE-Cy5, APC
|
| CD46
|
MCP
|
56/66kD
|
CCRSF
|
nucleated cells
|
membrane cofactor protein, binds C3b & C4b allowing
degradation by Factor I, measles virus receptor
|
|
|
| CD47
|
IAP
|
47-52kD
|
IgSF
|
hematopoietic cells, epith, endoth, fibroblasts, other
tissues
|
leukocyte adhesion, migration, activation
|
|
|
| CD47R
|
|
|
|
New designation for CDw149, similar distribution as
CD47 but dimmer
|
|
|
|
| CD48
|
Blast-1
|
45kD
|
IgSF
|
broad, all leukocytes
|
cell adhesion
|
|
|
| CD49a
|
VLA-1
|
210kD
|
Integrin family
|
Tact, mono
|
integrin α1, adhesion, CD49a/CD29
binds collagen and laminin
|
|
|
| CD49b
|
VLA-2
|
165kD
|
Integrin family
|
B, mono, platelets, Tact, megakaryocytes
|
integrin α2, adhesion, CD49b/CD29
binds collagen and laminin
|
eBioY418
|
PU, FG, F
|
| CD49c
|
VLA-3
|
125kD
|
Integrin family
|
B and Tlow, most adhesive cell lines
|
integrin α3, adhesion, CD49c/CD29 binds laminin,
fibronectin and collagen
|
mAb (please inquire)
|
|
| CD49d
|
VLA-4
|
150kD
|
Integrin family
|
T, B, NK, thymocytes, mono, eosinophils, mast, DC
|
integrin α4, adhesion, CD49d/CD29 binds fibronectin,
VCAM-1 & MAdCAM-1
|
9F10
|
PU, FG, PE
|
| CD49e
|
VLA-5
|
135, 25kD
|
Integrin family
|
thymocytes, T, mono, platelets, early and Bact
|
integrin α5, adhesion, CD49e/CD29
binds fibronectin
|
|
|
| CD49f
|
VLA-6
|
125kD
|
Integrin family
|
memory T, thymocytes, mono,
platelets, megakaryocytes, epith
|
integrin α6, adhesion,
CD49f/CD29
binds laminin
|
|
|
| CD50
|
ICAM-3
|
110-120kD
|
IgSF
|
hematopoietic, endoth, epidermal Langerhans cells
|
adhesion, costimulation
|
TP1/25.1
|
PU, F, PE
|
| CD51
|
Vitronectin receptor
|
125, 24kD
|
Integrin family
|
plateletslow, endoth, osteoblasts,
melanomas
|
integrin αv, adhesion, CD51/CD61 binds
vitronectin, vWF, fibrinogen and thrombospondin
|
23C6
|
PU, FG, B, F
|
| CD52
|
CAMPATH-1
|
21-28kD
|
|
thymocytes, T, B (not plasma cells), mono, mac
|
|
|
|
| CD53
|
|
35-42kD
|
TM4SF
|
leukocytes, DC, osteoblasts, osteoclasts
|
signal transduction
|
|
|
| CD54
|
ICAM-1
|
90-110kD
|
IgSF
|
endoth, mono, lymph (high upon activation)
|
receptor for CD11a/CD18 (LFA-1), CD11b/CD18
(Mac-1) and rhinovirus
|
HA58
|
PU, FG, B, PE
|
| CD55
|
DAF
|
60-70kD
|
GPI-linked
|
hematopoietic, endoth
|
binds C3b, complement regulation
|
143-30
|
PU, B, F, PE
|
| CD56
|
NCAM
|
175-185kD
|
IgSF
|
NK, T subset, neurons, some large granular
lymphocyte leukemias, myeloid leukemias
|
adhesion
|
MEM188
|
PU, FG, F, PE, PE-Cy5.5
|
| CD57
|
HNK-1, Leu-7
|
110kD
|
|
NK subset, T subset
|
|
TB01
|
F
|
| CD58
|
LFA-3
|
55-70kD
|
IgSF
|
hematopoietic, non-hematopoietic cells
|
CD2 receptor, adhesion
|
|
|
| CD59
|
Protectin, MAC- inhibitor
|
19kD
|
GPI-linked
|
hematopoietic, non-hematopoietic cells
|
binds complement C8 and C9, blocks assembly of
membrane attack complex
|
MEM-43
|
F, PE
|
| CD60a
|
GD3
|
|
CHO
|
T subset, platelets, thymic epith, astrocytes
|
costimulation
|
|
|
| CD60b
|
9-O-sialyl GD3
|
|
CHO
|
T subset, Bact
|
|
|
|
| CD60c
|
7-O-sialyl GD3
|
|
CHO
|
T subset
|
|
|
|
| CD61
|
GPIIIa
|
105kD
|
Integrin family
|
platelets, megakaryocytes, mac, endoth
|
integrin β3, adhesion, CD41/CD61 or CD51/CD61
mediate adhesion to ECM
|
23C6
|
PU, FG, B, F
|
| CD62E
|
E-selectin, ELAM-1
|
97,107-115kD
|
Selectin
family
|
endoth
|
binds CD15s, cell rolling, metastasis
|
|
|
| CD62L
|
L-selectin, LECAM-1
|
74, 95kD
|
Selectin family
|
B, naīve and memory T, mono, gran, NK, thymocytes
|
CD34, GlyCAM, and MAdCAM-1 receptor, leukocyte
homing, tethering, rolling
|
Dreg56
|
PU, FG, F, PE, PE-Cy5, PE-Cy7, APC, APC-Tandem
|
| CD62P
|
P-selectin, PADGEM
|
140kD
|
Selectin family
|
activated platelets, endoth
|
CD162, CD15s receptor, adhesion, neutrophil rolling,
platelet-neutrophil and platelet-mono interactions
|
AK-4
|
PU, FG, F, PE
|
| CD63
|
LIMP, LAMP-3
|
53kD
|
TM4SF
|
activated platelets, mono, mac
|
lysosomal membrane protein, moves to cell surface
after activation
|
|
|
| CD64
|
FcγRI
|
72kD
|
IgSF
|
mono, mac, DC, Interferon or G-CSF activated gran
|
high affinity receptor for IgG, phagocytosis and ADCC
|
10.1
|
PU, FG, F, PE
|
| CD65
|
|
|
|
gran, mono subset, myeloid leukemias
|
|
|
|
| CD65s
|
VIM2
|
|
|
gran, mono, myeloid leukemias
|
phagocytosis
|
|
|
| CD66a
|
BGP-1, NCA-160
|
160-180kD
|
IgSF, CEA family
|
neutrophils, epith
|
cell adhesion
|
|
|
| CD66b
|
CD67, CGM6
|
95-100kD
|
IgSF, CEA family
|
gran
|
cell adhesion, neutrophil activation
|
|
|
| CD66c
|
NCA
|
90kD
|
IgSF, CEA family
|
neutrophils, colon carcinoma
|
cell adhesion
|
|
|
| CD66d
|
CGM1
|
35kD
|
IgSF, CEA family
|
neutrophils
|
|
|
|
| CD66e
|
CEA
|
180-200kD
|
IgSF, CEA family
|
colon epith, colon cancer
|
cell adhesion
|
|
|
| CD66f
|
PSG, Sp-1
|
54-72kD
|
IgSF, CEA family
|
pregnancy specific glycoprotein, placental
syncytiotrophoblasts, fetal liver
|
immune regulation, protects fetus from maternal
immune system
|
|
|
| CD68
|
Macrosialin, gp110
|
110kD
|
Sialomucin
|
intracellularly in mono, mac, neutrophils, basophils,
large lymph, mast cells, DC, myeloid progenitors, liver
|
|
eBioY1/82A
|
|
| CD69
|
AIM
|
28, 32kD
|
C-type lectin
|
Tact, B, NK and gran, thymocytes, platelets,
Langerhans cells
|
signal transduction
|
FN50
|
PU, B, F, PE, PE-Cy7, APC
|
| CD70
|
Ki-24
|
50, 70, 90, 160kD
|
TNFSF
|
Bact and Tact
|
CD27 ligand, T and B cell costimulation
|
|
|
| CD71
|
T9
|
95kD
|
|
proliferating cells, reticulocytes, erythroid precursors
|
transferrin receptor, iron uptake
|
T56/14
|
PU, F, PE
|
|
|
|
|
|
|
|
OKT9
|
PU, FG, B, F, PE
|
| CD72
|
Lyb-2
|
42kD
|
C-type lectin
|
B, FDC
|
CD5, CD100 receptor, B proliferation
|
|
|
| CD73
|
|
69kD
|
GPI-linked
|
B subset, T subset, FDC, epith
|
ecto-5-nucleotidase, nucleoside uptake,
T costimulation, lymph adhesion
|
|
|
| CD74
|
Ii, invariant chain
|
33, 35, 41, 43kD
|
|
B, mac, mono, Langerhans cells, DC, Tact
|
MHC class II traffic and function
|
|
|
| CD75
|
|
|
CHO Sialoglycan family
|
B subset, epith
|
lactosamines
|
|
|
| CD75s
|
|
|
CHO Sialoglycan family
|
B subset, T subset
|
α-2,6-sialylated lactosamines (previously CDw75
and CDw76)
|
|
|
| CD77
|
Gb3, Pk blood group
|
|
|
germinal center B, Burkitts lymphomashigh, follicular
lymphomaslow
|
apoptosis
|
|
|
| CD79a
|
Iga
|
33, 45kD
|
IgSF
|
B
|
component of BCR, BCR surface expression and
signal transduction
|
|
|
| CD79b
|
Igb
|
37kD
|
IgSF
|
B
|
component of BCR, BCR surface expression and
signal transduction
|
SN8
|
PU, F, PE
|
| CD80
|
B7, B7-1, BB1
|
60kD
|
IgSF
|
Bact and Tact, mac, DC
|
binds to CD28, CD152, T costimulation
|
2D10.4
|
PU, FG, B, F, PE, PE-Cy5
|
| CD81
|
TAPA-1
|
26kD
|
TM4SF
|
T, B, NK, thymocytes, DC, endoth, fibroblast,
neuroblastomas, melanomas
|
complex w/ CD19 & CD21, signaling, T costimulation
|
|
|
| CD82
|
R2
|
50-53kD
|
TM4SF
|
leukocytes
|
signal transduction
|
53H5
|
PU, FG, F
|
| CD83
|
HB15
|
43kD
|
IgSF
|
Bact and Tact, DC, Langerhans cells
|
|
HB15e
|
PU, B, F, PE
|
| CDw84
|
|
73kD
|
|
mono, platelets, B, T subset, mac subset
|
|
|
|
| CD85
|
|
110kD
|
IgSF, ILT/LIR family
|
DC, mono, B, NK, T subset
|
inhibition of NK, T cell cytolytic function
|
|
|
| CD86
|
B70, B7-2
|
80kD
|
IgSF
|
mono, DC, Bact and Tact
|
binds to CD28, CD152, T costimulation
|
IT2.2
|
PU, FG, B, PE, PE-Cy5
|
| CD87
|
UPA-R
|
39-66kD
|
GPI-linked
|
gran, mono, NK, Tact, endoth,
fibroblasts
|
urokinase plasminogen
activator receptor,
inflammatory cell invasion,
metastasis
|
|
|
| CD88
|
C5aR
|
40kD
|
TM7SF
|
gran, mono, DC
|
C5a receptor,
granulocyte activation
|
|
|
| CD89
|
FcαR
|
55-75kD
|
IgSF
|
mono, mac, gran, neutrophils,
B subset, T subset
|
IgA receptor, phagocytosis,
degranulation, respiratory burst
|
|
|
| CD90
|
Thy-1
|
25-35kD
|
IgSF, GPI-linked
|
CD34+ hematopoietic subset, neurons
|
hematopoietic stem cell and neuron differentiation
|
|
|
| CD91
|
|
600kD
|
LDLR family
|
mono, mac, neurons, fibroblasts
|
receptor for α-2-macroglobulin
|
|
|
| CDw92
|
|
70kD
|
|
neutrophils, mono, platelets, endoth, fibroblasts
|
|
|
|
| CD93
|
|
120kD
|
|
neutrophils, mono, endoth
|
|
mAb (please inquire)
|
PU, B, APC
|
| CD94
|
KP43
|
43kD
|
C-type lectin
|
NK, T subset
|
complex w/ NKG2, inhibits NK function
|
DX22
|
PU, F, PE
|
| CD95
|
Apo-1, Fas
|
45kD
|
TNFRSF
|
lymph (high upon activation), mono, neutrophils
|
FasL (CD178) receptor, apoptosis
|
DX2
|
PU, B, F, PE, PE-Cy5
|
|
|
|
|
|
|
|
EOS9.1
|
PU, FG
|
| CD96
|
TACTILE
|
160kD
|
IgSF
|
NK, Tact
|
adhesion of activated T and NK
|
|
|
| CD97
|
|
74, 80, 90kD
|
TM7SF
|
Bact and Tact, mono, gran
|
|
|
|
| CD98
|
4F2
|
80, 40kD
|
|
T, B, NK, gran, all human cell lines
|
cellular activation
|
|
|
| CD99
|
MIC2, E2
|
32kD
|
|
leukocytes
|
T cell activation, adhesion
|
3B2/TA8
|
PU, F, PE
|
| CD99R
|
E2
|
32kD
|
|
T, NK, myeloid cells
|
isoform of CD99
|
|
|
| CD100
|
|
150kD
|
|
hematopoietic cells except
immature bone marrow
cells, RBC and platelets
|
cell adhesion,
cellular activation
|
|
|
| CD101
|
V7, p126
|
120kD
|
IgSF
|
mono, gran, DC, Tact
|
T cell activation
|
|
|
| CD102
|
ICAM-2
|
55-65kD
|
IgSF
|
lymph, mono, platelets,
endoth
|
binds CD11a/CD18,
costimulation
|
|
|
| CD103
|
HML-1, α6, integrin αE
|
150, 25kD
|
Integrin family
|
intraepithelial lymph, lymph subset, activated lymph
|
w/ integrin β7, binds E-cadherin,
lymph homing/retention
|
B-Ly7
|
PU, F, PE
|
| CD104
|
β4 integrin
|
220kD
|
Integrin family
|
epith, Schwann cells, keratinocytes, some tumor cells
|
w/ integrin α6 (CD49f), cell adhesion,
differentiation, metastasis
|
|
|
| CD105
|
Endoglin
|
95kD
|
homodimer
|
endoth, bone marrow subset, activated mac
|
cellular response to TGF-β1
|
SN6
|
PU, FG, PE, APC
|
| CD106
|
VCAM-1
|
110kD
|
IgSF
|
activated endoth, FDC
|
VLA-4(CD49d/CD29) receptor, leukocyte adhesion,
migration, costimulation
|
STA
|
PU, B, PE
|
| CD107a
|
LAMP-1
|
110kD
|
|
activated platelets, T, endoth, metastatic tumors
|
a lysosomal membrane protein
|
eBioH4A3 (H4A3)
|
PU, B, F, PE-PE-Cy5, Alexa FluorŽ 488, Alexa FluorŽ 647
|
| CD107b
|
LAMP-2
|
120kD
|
|
activated platelets, T, endoth, metastatic tumors
|
a lysosomal membrane protein
|
eBioH4B4 (H4B4)
|
PU, B, F, Alexa FluorŽ 488, Alexa FluorŽ 647
|
| CD108
|
|
80kD
|
|
erythrocytes, lymphoblasts, resting lymphlow
|
|
|
|
| CD109
|
|
170kD
|
|
Tact and platelets, CD34+ subset, endoth
|
|
|
|
| CD110
|
MPL, TPO-R
|
82-84kD
|
CRSF
|
megakaryocytes, platelets, some CD34+ stem cellslow
|
thrombopoietin receptor, megakaryocyte progenitor
cell growth/differentiation
|
|
|
| CD111
|
PRR1, Nectin-1
|
64-72kD
|
IgSF
|
stem cell subset, mac, neutrophils
|
|
|
|
| CD112
|
PRR2, Nectin-2
|
64-72kD
|
IgSF
|
mono, neutrophils, CD34+ subset, megakaryocytes,
endoth, epith
|
intercellular adhesion
|
|
|
| CDw113
|
PVRL3, Nectin3
|
83kD
|
IgSF
|
testis, placenta
|
adhesion molecule that interacts with afadin
|
|
|
| CD114
|
G-CSFR
|
95, 139kD
|
CRSF
|
myeloid progenitors, endoth
|
myeloid differentiation/proliferation
|
|
|
| CD115
|
M-CSFR, c-fms
|
150kD
|
IgSF, RTK family
|
mono, mac, monocytic progenitors
|
CSF-1R, monocytic differentiation/ proliferation
|
12-3A3-1B10
|
PU, B, PE
|
| CD116
|
GM-CSFRα
|
70-85kD
|
CRSF
|
mono, gran, DC, endoth
|
w/ common β, myeloid differentiation/proliferation
|
4H1
|
PU, B, F, PE
|
| CD117
|
c-kit, SCFR
|
145kD
|
IgSF, RTK family
|
hematopoietic progenitors, mast cells
|
SCF receptor, hematopoietic progenitor development/differentiation
|
YB5.B8
|
PU, B, PE
|
| CD118
|
LIFR, gp190
|
190kD
|
Type I CRSF &
secreted forms
|
epithelial cells in adult and embryo
|
membrane-bound involved in signal transduction, soluble form inhibits activity of LIF
|
|
|
| CDw119
|
IFNγR
|
90-100kD
|
|
mac, mono, B, T, NK, neutrophils, endoth
|
IFN-γ Rα, w/ IFN-γ AF-1, host defense
|
|
|
| CD120a
|
TNFR-I
|
50-60kD
|
TNFRSF
|
hematopoietic, non-hematopoietic cells
|
receptor for both TNF-α and TNF-β
|
|
|
| CD120b
|
TNFR-II
|
75-85kD
|
TNFRSF
|
hematopoietic, non-hematopoietic cells
|
receptor for both TNF-α and TNF-β
|
|
|
| CD121a
|
IL-1R type I
|
80kD
|
IgSF
|
dimly expressed on many cells
|
binds IL-1α and IL-1β, IL-1 signaling
|
|
|
| CDw121b
|
IL-1R, type II
|
60-70kD
|
IgSF
|
B, mac, mono, T subset
|
binds IL-1α and IL-1β, negative signals
|
|
|
| CD122
|
IL-2Rβ
|
75kD
|
CRSF
|
NK, T, B, mono
|
IL-2Rβ and IL-15Rβ, signal transduction
|
|
|
| CDw123
|
IL-3R
|
70kD
|
CRSF
|
lymph subset, basophils, hematopoietic progenitors,
mac, DC, megakaryocytes
|
IL-3Rα, w/ CDw131
|
6H6
|
PU, B, PE, PE-Cy7
|
| CD124
|
IL-4R
|
140kD
|
CRSF
|
lymphlow, mono, hematopoietic
precursors, .broblast, epith
|
IL-4Rα, w/ CD132 or IL-13Rα, T cell
growth/differentiation
|
X2/45-12
|
PU, FG
|
| CDw125
|
IL-5R
|
60kD
|
CRSF
|
eosinophils, basophils
|
IL-5Rα, w/ CDw131
|
|
|
| CD126
|
IL-6R
|
80kD
|
IgSF, CRSF
|
Bact and plasma cells, most leukocyteslow, fibroblasts
|
IL-6Rα, w/ CD130
|
|
|
| CD127
|
IL-7R
|
65-75kD
|
CRSF
|
T, pro-B
|
IL-7Rα, w/ CD132, B and T cell development
|
eBioRDR5
|
PU, FG, B, F, Alexa FluorŽ 647, Pacific BlueŽ
|
| CDw128
|
see CD181 & CD182
|
|
|
|
|
|
|
| CD130
|
IL-6Rβ, gp130
|
130kD
|
CRSF
|
Bact and plasma cells, most leukocyteslow, endoth
|
IL-6Rβ, IL-6, IL-11, LIF, CNF signals
|
|
|
| CDw131
|
IL-3R common β
|
95-120kD
|
CRSF
|
mono, gran, early B
|
w/ α subunits of IL-3R, IL-5R, and
GM-CSFR, signal transduction
|
1C1
|
PU, PE
|
| CD132
|
Common γ
|
64kD
|
CRSF
|
T, B, NK, mono, gran
|
subunit of IL-2R, IL-4R, IL-7R, IL-9R, and IL-15R,
signal transduction
|
mAb (please inquire)
|
PU
|
| CD133
|
AC133, prominin-like 1
|
120kD
|
TM5SF
|
hematopoietic stem cell subset, epith, endoth
|
|
|
|
| CD134
|
OX-40
|
48-50kD
|
TNFRSF
|
Tact
|
T cell activation, differentiation, apoptosis
|
ACT35
|
PU, F, PE, APC
|
| CD135
|
Flt3/Flk2
|
130-150kD
|
RTK family
|
myelomonocytic, primitive B progenitors
|
tyrosine kinase, binds FLT3 ligand, early lymph
development
|
BV10A4H2
|
PU, B, F, PE, APC
|
| CDw136
|
MSP-R, RON
|
180kD
|
RTK family
|
epith, CNS, PNS, hematopoietic subset
|
migration, morphological change and proliferation
of different target cells
|
|
|
| CDw137
|
4-1BB
|
30kD
|
TNFRSF
|
Tact
|
T costimulation
|
|
|
| CD138
|
Syndecan-1
|
80-150kD
|
Syndecan family
|
plasma cells, pre-B, basolateral surface of epith, meurons
|
receptor for ECM, cell morphology
|
DL-101
|
PU, F, PE
|
| CD139
|
|
228kD
|
|
B, mono, gran, erythrocyteslow
|
|
|
|
| CD140a
|
PDGFRα
|
180kD
|
RTK family
|
fibroblasts, smooth muscle & glial cells, chondrocytes
|
binds PDGF A and B
|
|
|
| CD140b
|
PDGFRβ
|
180kD
|
RTK family
|
fibroblasts, smooth muscle & glial cells, chondrocytes
|
binds PDGF B
|
|
|
| CD141
|
Thrombomodulin
|
100kD
|
C-type lectin
|
mono, neutrophils, endoth, smooth muscle cells
|
initiation of protein C anticoagulant signal
|
|
|
| CD142
|
Tissue Factor
|
45kD
|
|
mono, endoth,
keratinocytes, epith
|
binds clotting factor VIIa,
initiator of clotting
|
|
|
| CD143
|
ACE
|
170kD
|
|
endoth, epith, neurons,
fibroblasts, activated mac
|
angiotensin converting
enzyme, angiotensin II
& bradykinin metabolism
|
|
|
| CD144
|
VE-Cadherin,
Cadherin-5
|
130kD
|
Cadherin family
|
endoth
|
adhesion, cell-cell
interaction
|
16B1
|
PU, B, PE
|
| CDw145
|
|
110, 90kD
|
|
endoth, some
stromal cells
|
|
|
|
| CD146
|
MUC18, S-endo
|
113-118kD
|
IgSF
|
endoth, melanomas, FDC, Tact
|
adhesion
|
|
|
| CD147
|
Neurothelin, basoglin
|
|
IgSF
|
leukocytes, erythrocytes, platelets, endoth
|
adhesion
|
|
|
| CD148
|
HPTP-eta
|
240-260kD
|
|
gran, mono, DC, T (high upon activation)
|
tyrosine phosphatase R Type III
|
|
|
| CD150
|
SLAM
|
75-95kD
|
IgSF
|
T subset (high upon activation), B, DC, endoth
|
costimulation, proliferation, Ig production, measles
virus receptor
|
A12 (7D4)
|
PU, FG, B, F, PE
|
| CD151
|
PETA-3
|
32kD
|
|
endoth, megakaryocytes, platelets, epith
|
cell adhesion
|
mAb (please inquire)
|
|
| CD152
|
CTLA-4
|
33kD
|
IgSF
|
Tact and B
|
CD80 and CD86 receptor, negative regulation of T cell
costimulation
|
14D3
|
PU, FG, B, PE
|
|
|
|
|
|
|
|
eBio20A
|
PU, FG, B, PE
|
| CD153
|
CD30L
|
40kD
|
TNFSF
|
neutrophils, B, Tact and mac
|
CD30 ligand, T costimulation
|
|
|
| CD154
|
CD40L, gp39, TRAP
|
32-39kD
|
TNFSF
|
Tact
|
CD40 ligand, B and DC costimulation
|
24-31
|
PU, FG, F, PE
|
| CD155
|
PVR
|
80-90kD
|
IgSF
|
mono, mac, CD34+ thymocytes
|
Polio virus receptor (PVR)
|
|
|
| CD156a
|
ADAM8
|
69kD
|
|
neutrophils, mono
|
leukocyte extravasation
|
|
|
| CD156b
|
TACE/ADAM 17
|
100kD
|
|
broad
|
cleaves membrane proteins (TNF, TGFα)
to generate soluble forms
|
|
|
| CDw156c
|
ADAM10
|
98kD
|
Peptidase M12B family
|
lymphoid organs, peripheral blood leukocyte,
cartilage, chondrocytes and fetal liver
|
proteolytic cleavage of cell-surface molecules
including Notch, TNF-α, APP and ephrin-A2
|
polyclonal
|
|
| CD157
|
BST-1
|
42-45kD
|
|
gran, mono, B progenitors, endoth
|
ADP-ribosyl-cyclic ADP-ribose hydrolase activities,
pre-B cell growth
|
eBioSY11B5 (SY11B5)
|
PU, PE
|
| CD158a
|
p58.1
|
50-58kD
|
IgSF, KIR family
|
NK subset, T subset
|
inhibition of NK cell cytolytic activity, MHC class-I
specific NK receptor
|
|
|
| CD158b
|
p58.2
|
50-58kD
|
IgSF, KIR family
|
NK subset, T subset
|
inhibition of NK cell cytolytic activity, MHC class-I
specific NK receptor
|
|
|
| CD159a
|
NKG2A
|
43kD
|
|
T subset, NK
|
w/ CD94, NK cell receptor
|
|
|
| CD159c
|
NKG2C
|
40kD
|
Type II C-Type Lectin
|
NK
|
w/ MHC class I HLA-E molecules,
forms heterodimer with CD94
|
|
|
| CD160
|
BY55
|
27kD
|
IgSF
|
NK subset, T subset
|
costimulation
|
|
|
| CD161
|
NKR-P1A
|
40kD
|
C-type lectin
|
T subset, NK
|
NK cell-mediated cytotoxicity
|
|
|
| CD162
|
PSGL-1
|
120kD
|
Mucin family
|
mono, gran, most lymph
|
CD62P, CD62L ligand, adhesion, rolling
|
|
|
| CD162R
|
PEN-5
|
|
CHO
|
NK subset
|
|
|
|
| CD163
|
130kD
|
|
Scavenger receptor SF
|
mono, mac
|
|
eBioGHI/61 (GHI/61)
|
PU, B, PE
|
| CD164
|
MGC-24
|
80kD
|
epith, mono, lymphlow, bone marrow stromal cells,
CD34+ erythroid progenitors
|
hematopoietic progenitor cell-stromal cell interaction
|
|
|
|
| CD165
|
AD2, gp37
|
42kD
|
lymph subset, mono, immature thymocytes, platelets
|
adhesion, thymocyte-thymic epith interaction
|
|
|
|
| CD166
|
ALCAM
|
105kD
|
IgSF
|
neurons, mono, epith, fibroblasts, Tact
|
CD6 ligand, adhesion
|
|
|
| CD167a
|
DDR1
|
120kD
|
RTK family
|
epith, myoblasts
|
tyrosine kinase, adhesion to collagen
|
|
|
| CD168
|
RHAMM
|
84-88kD
|
|
mono, T subset, thymocyte subset, intracellularly in
breast cancer cells
|
adhesion, tumor migration, metastasis
|
|
|
| CD169
|
sialoadhesin, Siglec-1
|
185kD
|
IgSF,
sialoadhesins
|
tissue mac subset
|
adhesion, cell-cell and cell-matrix interactions, binds
CD227 on breast cancer cells and CD43 on T cells
|
|
|
| CD170
|
Siglec-5, CD33-like2
|
140kD
|
IgSF, sialoadhesins
|
Mac subset, neutrophils
|
adhesion
|
|
|
| CD171
|
L1
|
200-210kD
|
IgSF
|
CNS, PNS, glial cells, mono, T subset, B, DC, several
human tumor cells
|
kidney morphogenesis, lymph node architecture, T
costimulation, neurohistogenesis, homotypic
interaction, binds CD9, CD24, CD56, CD142,
CD166, integrins
|
|
|
| CD172a
|
SIRPγ
|
110kD
|
|
mono, T subset, stem cells
|
adhesion, complex w/ CD47
|
|
|
| CD172b
|
SIRPβ, SIRB1
|
50kD
|
IgSF
|
mono and DC
|
negative regulation of RTK-coupled signaling
|
|
|
| CD172g
|
SIRPγ, SIRPB2
|
45-50kD
|
IgSF, ASV
|
mRNA: liver and at lower levels in many tissues
|
binds CD47
|
|
|
| CD173
|
Blood group H type 2
|
|
CHO
|
erythrocytes, stem cell subset, platelets
|
|
|
|
| CD174
|
Lewis Y
|
|
CHO
|
stem cells subset, epith
|
|
|
|
| CD175
|
Tn
|
|
CHO
|
stem cells subset
|
|
|
|
| CD175s
|
Sialyl-Tn
|
|
CHO
|
erythroblasts
|
|
|
|
| CD176
|
Thomson Friedrenreich Ag
|
|
CHO
|
stem cell subset
|
|
|
|
| CD177
|
NB1
|
56-62kD
|
|
neutrophil subset
|
|
|
|
| CD178
|
FasL, CD95L
|
38-42kD
|
TNFSF
|
Tact, testis
|
CD95 ligand, apoptosis, immune privilege, soluble
form in serum
|
NOK-1
|
PU, FG, B, PE
| |
