Product Information

Contents: Polyclonal anti-human DR6
Catalog Number: 60-6633
Sizes: 50 ug, 100 ug
Storage Conditions: This product is supplied as Protein G purified IgG fraction in PBS containing 0.02% sodium azide. Store at 4°C, stable for 6 months. For long-term storage, store at –20°C.
Clone: Polyclonal
Isotype: Rabbit IgG

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
60-6633	Polyclonal antibody to human DR6	N/A	N/A	WB

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Description

The polyclonal antibody reacts with human DR6; the antibody was antibody was raised against a peptide of human DR6. DR6 (Death Receptor 6) is a novel member of the TNFR superfamily. The extracellular portion of DR6 has four TNFR-like cysteine rich motifs that are most related to those of osteoprotegerin (OPG) and TNFR2.

Applications Reported

For research use only, not for diagnostic or therapeutic use. This polyclonal antibody has been reported for use in immunoblotting (WB).

Applications Tested

This polyclonal antibody has been reported for use in detection of DR6 expression by Western blotting at 2-4 μg/ml dilution. Whole cell lysate from HeLa cells can be used as a positive control and an approximately 60-66 kDa band should be detected. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest.

References

Pan G, et al. FEBS Lett 431: 351-356 (1998).
Simonet WS, et al. Cell 89: 309-310 (1997).
Baker SJ, et al. Oncogene 12: 1-9 (1996).

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