Contents: Polyclonal anti-human DRAK1
Catalog Number: 60-6627
Storage Conditions: This product is supplied as Protein G purified IgG fraction in PBS containing 0.02% sodium azide. Store at 4°C, stable for 6 months. For long-term storage, store at –20°C.
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Description
DRAK1 and DRAK2 (Death Receptor Associated Kinase 1 and 2) share significant homology with ZIP kinase at the amino acid level. The kinase domains of both DRAKs, and ZIP kinase are homologous to DAP (Death-associated protein) kinase which is involved in the apoptotic signaling induced by IFN-γ.
Applications Reported
For research use only, not for diagnostic or therapeutic use. This polyclonal antibody has been reported for use in immunoblotting (WB). It has been raised against a peptide corresponding to amino acids 5 to 19 of human DRAK1 protein.
Applications Tested
This antibody can be used for detection of DRAK1 expression by Western blotting at a 1-2 μg/ml dilution. Whole cell lysate from HeLa cells can be used as positive control. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
References
Sanjo H, et al. J Biol Chem 273: 29066-071 (1998).
Matsumoto M, et al. Mol Cell Biol 18: 1642;1651 (1998).
