Contents: Allophycocyanin (APC) anti-human CD105 (Endoglin)
Catalog Number: 17-1057
Formulation: Phosphate buffer pH 7.2, 150 mM NaCl, 0.09% NaN3, 0.2% BSA
Storage Conditions: Store at 4°C. DO NOT FREEZE. LIGHT-SENSITIVE MATERIAL.
Clone: SN6
Isotype: Mouse IgG1
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Staining of U937 cells with APC Mouse IgG1, K Iso Cntrl (cat. 17-4714) (open histogram) or APC anti-human CD105 (SN6) (colored histogram). Total viable cells were used for analysis.
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Description
The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin. CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages. It is suggested that CD105 functions in adhesion and embryonic angiogenesis.
Applications Reported
For research use only, not for diagnostic or therapeutic use. The SN6 antibody has been reported for use in flow cytometric analysis.
Applications Tested
This SN6 antibody has been pre-titrated and tested by flow cytometric analysis of U937 cell line. This can be used at 5 μl (0.5 μg) per million cells in a 100 μl total staining volume.
References
Kishimoto, T., A.E.G., von dem Borne, et al. eds. 1998. Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing Inc. London.
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Cat.
17-4714 Allophycocyanin (APC) Mouse IgG1, K Isotype Control