Contents: Allophycocyanin (APC) anti-human CD11b (Integrin alpha M, Mac-1 alpha)
Catalog Number: 17-0118
Formulation: Phosphate buffered saline, pH 7.2, less than or equal to 0.09% NaN3, BSA and/or gelatin for protein stabilization
Storage Conditions: Store at 4°C.
DO NOT FREEZE.
LIGHT-SENSITIVE MATERIAL.
Clone: ICRF44
Isotype: Mouse IgG1, κ
HLDA No.: IV M047
| Prices for This Product* |
| Cat. No. |
Size |
Price |
Qty |
Action |
*International customers: Please contact your distributor for region specific pricing.
|
|
Staining of normal human peripheral blood cells with 0.5 μg of APC Mouse IgG1, K Iso Cntrl (cat. 17-4714) (blue histogram) or APC anti-human CD11b (ICRF44) (purple histogram). Cells in the monocyte (left) and granulocyte (right) gates were used for analysis.
|
Questions? Please consult our answers to frequently asked questions at
http://www.ebioscience.com/faq.
Description
The ICRF44 monoclonal antibody reacts with human CD11b, a 165 kDa adhesion molecule. CD11b associated with integrin β
2 (CD18) is expressed on the surface of monocytes, granulocytes, activated lymphocytes and a subset of NK cells. CD11b is a receptor for intercellular adhesion molecule family members CD54, CD102 and CD50 as well as for iC3b. These adhesions are crucial in cell-cell and cell-matrix interactions.
Applications Reported
For research use only, not for diagnostic or therapeutic use. This ICRF44 antibody has been reported for use in flow cytometric analysis.
Applications Tested
This ICRF44 antibody has been pre-titrated and tested by flow cytometric analysis of normal human blood cells. This can be used at 20 μl (0.5 μg) per million cells in a 100 μl total staining volume.
References
Knapp, W., B. Dorken, et al. eds. (1989). Leucocyte Typing IV: White Cell Differentiation Antigens. Oxford University Press. New York.
Related Products
Cat.
17-0112 APC anti-mouse CD11b (Integrin alpha M, Mac-1 alpha) (clone M1/70)
Cat.
17-4714 Allophycocyanin (APC) Mouse IgG1, K Isotype Control
Human Cellular Antigens Chart