Product Information
Contents: Affinity Purified anti-human DR5 (CD262, Trail-R2, TrailR2)
Catalog Number: 14-9909
Sizes: 25 ug, 100 ug
Formulation: Phosphate buffer pH 7.2, 150 mM NaCl, 0.09% NaN3
Storage Conditions: Store at 4°C. Avoid repeated freeze/thaw cycles.
Clone: DJR2-2 (a.k.a. 2-6)
Isotype: Mouse IgG1, κ
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| Available Formats of This Product |
| Cat. No. |
Format |
Excite (nm) |
Emit (nm) |
Reported Applications |
| 14-9909 |
Affinity Purified anti-human DR5 (CD262, Trail-R2, TrailR2) |
N/A |
N/A |
FC
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Flow Cytometry Product Notes: Test Sizes: To accommodate multicolor flow cytometry, eBioscience is in the process of reducing test size volumes from 20 µl to 5 µl. Please check your antibody vial for the recommended test size. Fluorochrome Replacements: eBioscience is in the process of replacing all Pacific Blue® and APC-Alexa Fluor® 750 conjugated products with eFluor™ 450 and APC-eFluor™ 780 conjugated products, respectively. |
Questions? Please consult our answers to frequently asked questions at
http://www.ebioscience.com/faq.
Description
The DJR2-2 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-κB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells.
Applications Reported
For research use only, not for diagnostic or therapeutic use. The DJR2-2 (a.k.a. 2-6) antibody has been reported for use in flow cytometric analysis.
Applications Tested
The DJR2-2 (a.k.a. 2-6) antibody has been tested by flow cytometric analysis of human MOLT-4 cells and human DR5-transfected cells. This can be used at less than or equal to 1 μg per million cells in a 100 μl total staining volume. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Related Products
Cat. 11-4011 FITC Anti-Mouse IgGCat. 13-4013 Biotin Anti-Mouse IgG (clone Polyclonal)Cat. 11-4317 Streptavidin-FITC (Fluorescein isothiocyanate)Cat. 12-4317 Streptavidin-PE (Phycoerythrin)Cat. 17-4317 Streptavidin Allophycocyanin (SA-APC)Cat. 14-4714 Affinity Purified Mouse IgG1, K Isotype ControlCat. 12-9908 PE anti-human DR5 (CD262, Trail-R2, TrailR2) (clone DJR2-4 (a.k.a. 7-8))Cat. 13-9908 Biotin anti-human DR5 (CD262, Trail-R2, TrailR2) (clone DJR2-4 (a.k.a. 7-8))Cat. 14-9908 Affinity Purified anti-human DR5 (CD262, Trail-R2, TrailR2) (clone DJR2-4 (a.k.a. 7-8))