anti-Human DR5: Human DR5 (Trail-R2, TrailR2) antibody

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Contents: Affinity Purified anti-human DR5 (CD262, Trail-R2, TrailR2)
Catalog Number: 14-9909
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN₃
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Clone: DJR2-2 (a.k.a. 2-6)
Isotype: Mouse IgG1, κ

Prices for This Product*
Cat. No.	Size	Price	Qty	Action
14-9909-80	25 ug	$95
14-9909-82	100 ug	$195

*International customers: Please contact your distributor for region specific pricing.

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
14-9909	Affinity Purified anti-human DR5 (CD262, Trail-R2, TrailR2)	N/A	N/A	FC

Questions? Please consult our answers to frequently asked questions at http://www.ebioscience.com/faq.

Description

The DJR2-2 monoclonal antibody reacts with human DR5, also known as TRAIL-R2, Apo2, TRICK2, and KILLER. DR5 binds to TRAIL, activates NF-κB, and induces TRAIL-mediated apoptosis. DR5 is expressed broadly by normal tissues as well as several tumor cells.

Applications Reported

For research use only, not for diagnostic or therapeutic use. The DJR2-2 (a.k.a. 2-6) antibody has been reported for use in flow cytometric analysis.

Applications Tested

The DJR2-2 (a.k.a. 2-6) antibody has been tested by flow cytometric analysis of human MOLT-4 cells and human DR5-transfected cells. This can be used at less than or equal to 1 μg per million cells in a 100 μl total staining volume. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

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