Contents: Affinity Purified anti-mouse Toll-like receptor 11 (TLR11, TLR-11)
Catalog Number: 14-9119
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN3
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Clone: Polyclonal
Isotype: Rabbit IgG
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Description
The polyclonal antibody reacts with mouse TLR11 and was generated using 16 amino acid residues near the middle of mouse TLR11. To date, at least twelve members of the Toll family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immunity system, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune responses. TLR11 is reported to bind and respond to uropathogenic bacteria. Immunoblotting with this antibody gives a MW of ~95 kDa in RAW264.7 cells.
Applications Reported
For research use only, not for diagnostic or therapeutic use. Rabbit anti-mouse TLR11 poly has been reported for use in immunoblotting (WB).
Applications Tested
Rabbit anti-mouse TLR11 poly has been tested by immunoblotting (WB) of RAW264.7 cell lystae (1-2ug/ml). It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
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