Product Information

Contents: Affinity Purified anti-mouse Toll-like receptor 3 (CD283, TLR3, TLR-3)
Catalog Number: 14-9032
Sizes: 25 ug, 100 ug
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN₃
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Clone: T3.7C3
Isotype: Rat IgG2a

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
14-9032	Affinity Purified anti-mouse Toll-like receptor 3 (CD283, TLR3, TLR-3)	N/A	N/A	WB

Custom Product Requests
Need a custom product? Download the Custom Product Request Form and submit completed form to customs@ebioscience.com.

Questions? Please consult our answers to frequently asked questions at http://www.ebioscience.com/faq.

Description

The T3.7C3 antibody reacts with mouse TLR3 and was generated using the sequence of extracellular domain of mouse TLR3. To date, at least twelve members of the Toll family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immunity system, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune responses. TLR3 recognizes double-stranded (ds)RNA and induces the activation of NF-κB, through MyD88-dependent and -independent pathways and the production of type I interferons (IFNs). Immunoblotting with this antibody gives a MW of ~120 kDa in mTLR3 transfected cells.

Applications Reported

For research use only, not for diagnostic or therapeutic use. The T3.7C3 antibody has been reported for use in immunoblotting (WB).

Applications Tested

The T3.7C3 antibody has been tested by immunoblotting of mTLR3 transfected cell lysate and can be used at 1-3ug/ml.

Related Products

Cat. 11-4317  Streptavidin-FITC (Fluorescein isothiocyanate)
Cat. 12-4317  Streptavidin-PE (Phycoerythrin)
Cat. 17-4317  Streptavidin Allophycocyanin (SA-APC)
Cat. 14-4321  Affinity Purified Rat IgG2a Isotype Control
Cat. 11-4811  FITC Anti-Rat IgG
Cat. 13-4813  Biotin Anti-Rat IgG (clone Polyclonal)
Cat. 14-8185  Recombinant B18R protein (Vaccinia Virus-Encoded Neutralizing Type I Interferon Receptor; Type I IFN inhibitor)
Cat. 34-8185  Carrier-Free Recombinant B18R protein (Vaccinia Virus-Encoded Neutralizing Type I Interferon Receptor; Type I IFN inhibitor)
Cat. 11-8317  Fluorescein isothiocyanate (FITC) mouse anti-human IFN-alpha2 (clone 225.C)
Cat. 12-8317  Phycoerythrin (PE) mouse anti-human IFN-alpha2 (clone 225.C)
Cat. 17-8317  Allophycocyanin (APC) mouse anti-human IFN-alpha2 (clone 225.C)
Cat. 24-9031  Rat serum anti-mouse Toll-like receptor 3 (CD283, TLR3, TLR-3, polyclonal antibody) (clone Polyclonal)