Product Information

Contents: Affinity Purified anti-mouse/human/rat Bcl-x_L
Catalog Number: 14-6994
Sizes: 50 ug, 100 ug
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN₃
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Clone: 2H12
Isotype: Mouse IgG2a, κ

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
14-6994	Affinity Purified anti-mouse/rat/monkey/human Bcl-xL	N/A	N/A	WB

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Description

The 2H12 antibody reacts with the human, mouse and rat Bcl-x_L molecule, an approximately 27 kDa oncoprotein. Bcl-x_L functions as a central repressor of several apoptotic signals.

Applications Reported

For research use only, not for diagnostic or therapeutic use. The 2H12 antibody has been reported for use in immunoblotting (WB).

Applications Tested

The 2H12 antibody has been tested by Western blot analysis of HeLa lysate and can be used at less than 2 μg/ml. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest.

References

Hsu YT, et. al. Proceedings of the National Academy of Sciences of the United States of America, 1997, 94(8):3668-72.
Hsu YT, et. al. Journal of Biological Chemistry, 1997, 272(21):13829-34.

Related Products

Cat. 14-4724 Affinity Purified Mouse IgG2a, K Isotype Control
Cat. 18-8877 See Catalog # 18-8817 for an alternative product: Mouse TrueBlot™: Horseradish Peroxidase (HRP) anti-mouse IgG