Product Information

Contents: Affinity Purified Human/Mouse WASP Polyclonal Antibody
Catalog Number: 14-6887
Sizes: 10 ug, 50 ug
Formulation: Phosphate buffered saline, pH 7.2, less than or equal to 0.09% NaN₃
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Isotype: Goat IgG

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
14-6887	Affinity Purified Human/Mouse WASP Polyclonal Antibody	N/A	N/A	ELISA IHC WB

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Description

This polyclonal antibody reacts with Wiskott-Aldrich syndrome protein (WASP), which is a cytosolic adaptor protein mediating the rearrangement of the actin cytoskeleton upon surface receptor signaling. WASP is a 54 kDa protein belonging to the WASP/SCAR/WAVE family of proteins, and is expressed selectively in hematopoietic lineages. Mutations in WASP are associated with diseases of the hematopoietic/immunologic system.

Applications Reported

For research use only, not for diagnostic or therapeutic use. Purified Human/Mouse WASP Polyclonal has been reported for use in immunoblotting (WB), immunohistochemical staining, and ELISA.

Applications Tested

Purified Human/Mouse WASP Polyclonal has been tested by western blot analysis of K562 cell lysates. As a starting dilution, it is recommended that this polyclonal antibody be used at 2 μg/ml.

References

Derry JM, Ochs HD, Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell. 1994 Aug 26;78(4):635-44.

Derry JM, Wiedemann P, Blair P, Wang Y, Kerns JA, Lemahieu V, Godfrey VL, Wilkinson JE, Francke U. The mouse homolog of the Wiskott-Aldrich syndrome protein (WASP) gene is highly conserved and maps near the scurfy (sf) mutation on the X chromosome. Genomics. 1995 Sep 20;29(2):471-7.

Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, Mccormick F, Francke U, Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell. 1996 Mar 8;84(5):723-34.