Contents: Affinity Purified anti-human AITR Ligand
Catalog Number: 14-5876
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN3
Storage Conditions: Store at 4°C.
Avoid repeated freeze/thaw cycles.
Clone: EB11
Isotype: Mouse IgG1, κ
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Flow Cytometry Product Notes:
Test Sizes: To accommodate multicolor flow cytometry, eBioscience is in the process of reducing test size volumes from 20 µl to 5 µl. Please check your antibody vial for the recommended test size.
Fluorochrome Replacements: eBioscience is in the process of replacing all Pacific Blue® and APC-Alexa Fluor® 750 conjugated products with eFluor™ 450 and APC-eFluor™ 780 conjugated products, respectively. |
Questions? Please consult our answers to frequently asked questions at
http://www.ebioscience.com/faq.
Description
The EB11 monoclonal antibody reacts with human Activation-Induced TNFR family member ligand (AITRL), also known as TL6. AITRL is a type II transmembrane protein of the TNF superfamily. AITRL is expressed by endothelial cells and peripheral blood monocytes. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.
Applications Reported
For research use only, not for diagnostic or therapeutic use. The EB11 antibody has been reported for use in flow cytometric analysis, and immunoblotting (WB).
Applications Tested
The EB11 antibody has been tested by flow cytometric analysis. It is recommended that the reagent be carefully titrated for optimal performance in the assay of interest.
References
Kwon B, Yu KY, Ni J, Yu GL, Jang IK, Kim YJ, Xing L, Liu D, Wang SX, Kwon BS. 1999. J Biol Chem. 274(10):6056-61. Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.
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