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Human Cellular Antigens Chart

Contents: Affinity Purified anti-human CD43 (Leukosialin, Sialophorin) Catalog Number: 14-0439 Formulation: Phosphate buffered saline, pH 7.2, less than or equal to 0.09% NaN3 Storage Conditions: Store at 4°C. Avoid repeated freeze/thaw cycles. Clone: eBio84-3C1 (84-3C1) Isotype: Mouse IgG1 Prices for This Product* Cat. No. Size Price Qty Action 14-0439-80 25 ug $55 14-0439-82 100 ug $100 *International customers: Please contact your distributor for region specific pricing.

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
11-0439	Fluorescein isothiocyanate (FITC) anti-human CD43 (Leukosialin, Sialophorin)	488	518	FC
12-0439	Phycoerythrin (PE) anti-human CD43 (Leukosialin, Sialophorin)	488	575	FC
14-0439	Affinity Purified anti-human CD43 (Leukosialin, Sialophorin)	N/A	N/A	FC  WB
17-0439	Allophycocyanin (APC) anti-human CD43 (Leukosialin, Sialophorin)	633	660	FC

Questions? Please consult our answers to frequently asked questions at http://www.ebioscience.com/faq.

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Description

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The monoclonal antibody ebio84-3C1 reacts with CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin. CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions. Expression of CD43 is found on most leukocytes except resting B lymphocytes. Proteolytic processing upon activation decreases surface expression. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages.

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Applications Reported

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For research use only, not for diagnostic or therapeutic use. This eBio84-3C1 (84-3C1) antibody has been reported for use in flow cytometric analysis.

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Applications Tested

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This eBio84-3C1 (84-3C1) antibody has been tested by flow cytometric analysis of human peripheral blood cells.

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References

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Borche L, Lozano F, Vilella R, Vives J. CD43 monoclonal antibodies recognize the large sialoglycoprotein of human leukocytes. Eur J Immunol. 1987 Oct;17(10):1523-6.

Schlossman, S., L. Bloumsell, et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.

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Related Products

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Cat. 11-4011    FITC Anti-Mouse IgG
Cat. 13-4013    Biotin Anti-Mouse IgG (clone Polyclonal)
Cat. 11-4317    Streptavidin-FITC (Fluorescein isothiocyanate)
Cat. 12-4317    Streptavidin-PE (Phycoerythrin)
Cat. 17-4317    Streptavidin Allophycocyanin (SA-APC)
Cat. 14-4714    Affinity Purified Mouse IgG1, K Isotype Control