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Questions? Please consult our answers to frequently asked questions at http://www.ebioscience.com/faq. DescriptionThe 2A6 monoclonal antibody reacts with human CD26, a 110 kDa type II transmembrane dimer. CD26 is an ectoenzyme with dipeptidyl peptidase IV activity expressed by T cells and is upregulated upon T cell stimulation. It is thought that CD26 plays a role in interaction with the extracellular matrix molecules and in T cell activation. Applications ReportedFor research use only, not for diagnostic or therapeutic use. The 2A6 antibody has been reported for use in flow cytometric analysis. Applications TestedThe 2A6 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 1 μg per 100 μl blood (or per 1 million cells in 100 μl total staining volume). It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. References
Schlossman, S., L. Bloumsell, et al. eds. (1995).Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. Kishimoto, T., A.E.G., von dem Borne, et al. eds. (1998). Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing, Inc. London. Related ProductsCat. 11-4011 FITC Anti-Mouse IgG Cat. 13-4013 Biotin Anti-Mouse IgG (clone Polyclonal) Cat. 11-4317 Streptavidin-FITC (Fluorescein isothiocyanate) Cat. 12-4317 Streptavidin-PE (Phycoerythrin) Cat. 17-4317 Streptavidin Allophycocyanin (SA-APC) Cat. 14-4714 Affinity Purified Mouse IgG1, K Isotype Control |
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