Product Information

Contents: Biotin anti-human interleukin-1β (IL-1β)
Catalog Number: 13-7016
Sizes: 50 ug, 500 ug
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN₃
Storage Conditions: Store at 4°C.
DO NOT FREEZE.
Clone: CRM57
Isotype: Mouse IgG2b

Available Formats of This Product
Cat. No.	Format	Excite (nm)	Emit (nm)	Reported Applications
13-7016	Biotin anti-human IL-1b (Interleukin-1 beta, IL1b)	N/A	N/A	ELISA det

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Description

The CRM57 antibody reacts with human and baboon interleukin-1β (IL-1β). IL-1β is a 17 kDa factor secreted primarily by monocytes. IL-1 has effects on T-helper cells, inducing IL-2 secretion and expression of IL-2 receptors. IL-1 has effects on B cells, promoting cell proliferation and immunoglobulin synthesis.

Applications Reported

For research use only, not for diagnostic or therapeutic use. The CRM57 antibody has been reported for use in ELISA.

Applications Tested

The CRM57 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of human interleukin-1β (IL-1β) in combination with the purified CRM56 (14-7018) for capture and recombinant human IL-1β (14-8018) as the standard. A suitable range of concentrations of this antibody for use in ELISA detection is 0.25 -1 µg/ml. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/ml - 8 pg/ml should be included in each ELISA plate.

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