Contents: Biotin anti-human CD123 (interleukin-3 receptor α, IL-3Rα)
Catalog Number: 13-1239
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN3
Storage Conditions: Store at 4°C.
DO NOT FREEZE.
Clone: 6H6
Isotype: Mouse IgG1, κ
| Prices for This Product* |
| Cat. No. |
Size |
Price |
Qty |
Action |
*International customers: Please contact your distributor for region specific pricing.
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| Available Formats of This Product |
| Cat. No. |
Format |
Excite
(nm) |
Emit
(nm) |
Reported Applications |
| 11-1239 |
Fluorescein isothiocyanate (FITC) anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra) |
488 |
518 |
FC
|
| 12-1239 |
PE anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra, IL3Ra) |
488 |
575 |
FC
|
| 13-1239 |
Biotin anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra, IL3Ra) |
N/A |
N/A |
FC
|
| 14-1239 |
Affinity Purified anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra, IL3Ra) |
N/A |
N/A |
FC
IH/F
IHC(Paraffin)
|
| 17-1239 |
Allophycocyanin (APC) anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra, IL3Ra) |
633 |
660 |
FC
|
| 25-1239 |
Phycoerythrin-Cy7 (PE-Cy7) anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra, IL3Ra) |
488 |
760 |
FC
|
| 45-1239 |
PerCP-Cy5.5 anti-human CD123 (Interleukin-3 Receptor alpha, IL-3 Receptor alpha, IL-3Ra) |
488 |
690 |
FC
|
Questions? Please consult our answers to frequently asked questions at
http://www.ebioscience.com/faq.
Description
The 6H6 monoclonal antibody reacts with human CD123, the α chain of the IL-3 receptor. This 60-70 kDa transmembrane protein binds to IL-3 with low affinity by itself, and when associated with CD131 (common β chain) binds IL-3 with high affinity. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, and megakaryocytes.
Applications Reported
For research use only, not for diagnostic or therapeutic use. The 6H6 antibody has been reported for use in flow cytometric analysis.
Applications Tested
The 6H6 antibody has been tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at less than or equal to 0.25 μg per 100 μl blood (or per 1 million cells in 100 μl total staining volume). It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
References
Herling, M., M. Teitell, R. Shen, L. Medeiros, and D. Jones. 2003. TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin. Blood. 101: 5007-5009.
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Human Cellular Antigens Chart