Contents: Phycoerythrin (PE) anti-human CD26
Catalog Number: 12-0269
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN3, 0.2% BSA
Storage Conditions: Store at 4°C.
DO NOT FREEZE.
LIGHT-SENSITIVE MATERIAL.
Clone: 2A6
Isotype: Mouse IgG1, κ
HLDA No.: VI N-L167
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Surface staining of normal human peripheral blood cells with anti-human CD26 (2A6) FITC (left), and PE (right). Appropriate isotype controls were used (open histogram). Cells in the lymphocyte population were used for analysis.
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Description
The 2A6 monoclonal antibody reacts with human CD26, a 110 kDa type II transmembrane dimer. CD26 is an ectoenzyme with dipeptidyl peptidase IV activity expressed by T cells and is upregulated upon T cell stimulation. It is thought that CD26 plays a role in interaction with the extracellular matrix molecules and in T cell activation.
Applications Reported
For research use only, not for diagnostic or therapeutic use. The 2A6 antibody has been reported for use in flow cytometric analysis.
Applications Tested
The 2A6 antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at 20 μl (0.5 μg) per 100 μl blood (or per 1 million cells in 100 μl total staining volume).
References
Schlossman, S., L. Bloumsell, et al. eds. (1995).Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.
Kishimoto, T., A.E.G., von dem Borne, et al. eds. (1998). Leucocyte Typing VI: White Cell Differentiation Antigens. Garland Publishing, Inc. London.
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12-4714 Phycoerythrin (PE) Mouse IgG1, K Isotype Control
Human Cellular Antigens Chart