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Questions? Please consult our answers to frequently asked questions at http://www.ebioscience.com/faq. DescriptionThe CRM8 monoclonal antibody reacts with human interleukin-1α (IL-1α). IL-1α is a 17 kDa factor secreted primarily by monocytes. IL-1 has effects on T-helper cells, inducing IL-2 secretion and expression of IL-2 receptors. IL-1 has effects on B cells, promoting cell proliferation and immunoglobulin synthesis. For optimal detection of human IL-1α by ELISA, a combination of purified CRM8 antibody for capture and biotinylated CRM6 antibody for detection is recommended. Applications ReportedFor research use only, not for diagnostic or therapeutic use. The CRM8 antibody has been reported for use in intracellular flow cytometric analysis. Applications TestedThe CRM8 antibody has been tested by intracellular flow cytometric analysis. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Related ProductsCat. 11-4718 FITC Mouse IgG1, K Isotype Control (I/C Staining) Cat. 13-7017 Biotin anti-human IL-1a (Interleukin-1 alpha, IL1a) (clone CRM6) Cat. 14-8019 Recombinant Human IL-1a (Interleukin-1 alpha, IL1a) Cat. 00-8222 eBioscience IC Fixation Buffer Cat. 00-8333 eBioscience Permeabilization Buffer(10X) Cat. 88-8823 eBioscience Fixation & Permeabilization |
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