Contents: Fluorescein isothiocyanate (FITC) anti-human CD150 (SLAM, IPO-3)
Catalog Number: 11-1509
Formulation: Phosphate buffer pH 7.2,
150 mM NaCl, 0.09% NaN3, 0.2% BSA
Storage Conditions: Store at 4°C.
DO NOT FREEZE.
LIGHT-SENSITIVE MATERIAL.
Clone: A12 (7D4)
Isotype: Mouse IgG1, κ
HLDA No.: N/A
| Prices for This Product* |
| Cat. No. |
Size |
Price |
Qty |
Action |
*International customers: Please contact your distributor for region specific pricing.
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| Available Formats of This Product |
| Cat. No. |
Format |
Excite
(nm) |
Emit
(nm) |
Reported Applications |
| 11-1509 |
FITC anti-human CD150 (SLAM, IPO-3, IPO3) |
488 |
518 |
FC
|
| 12-1509 |
PE anti-human CD150 (SLAM, IPO-3, IPO3) |
488 |
575 |
FC
|
| 13-1509 |
Biotin anti-human CD150 (SLAM, IPO-3, IPO3) |
N/A |
N/A |
FC
|
| 14-1509 |
Affinity Purified anti-human CD150 (SLAM, IPO-3, IPO3) |
N/A |
N/A |
FA
FC
IHC
|
| 16-1509 |
Functional Grade* Purified anti-human CD150 (SLAM, IPO-3, IPO3) |
N/A |
N/A |
FA
FC
|
*Functional Grade™ (FG™) Purified: Azide-free, sterile-filtered, and endotoxin < 0.001 ng/µg (unless otherwise noted).
*Functional Grade™ (FG™) Biotin: Azide-free, sterile-filtered, and endotoxin < 0.05 ng/µg.
Purified: Contains azide, not sterile-filtered, and not endotoxin tested. |
Questions? Please consult our answers to frequently asked questions at
http://www.ebioscience.com/faq.
Description
The A12 monoclonal antibody reacts with human CD150, an ~70 kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T and B cells and its expression is rapidly upregulated on these cells upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM induces proliferation and cytokine production of T cells and SLAM plays a role in activation of T and B cells.
Applications Reported
For research use only, not for diagnostic or therapeutic use. A12 (7D4) has been reported for use in flow cytometric analysis.
Applications Tested
The A12 (7D4) antibody has been pre-titrated and tested by flow cytometric analysis of human peripheral blood leukocytes. This can be used at 20 μl (1 μg) per 100 μl blood (or per 1 million cells in 100 μl total staining volume).
References
Cocks, B. G., C. C. Chang, et al. (1995). "A novel receptor involved in T-cell activation."
Nature 376(6537): 260-3.
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11-4714 Fluorescein isothiocyanate (FITC) Mouse IgG1, K Isotype Control
Human Cellular Antigens Chart