**Starting now: ebioscience.com products are on thermofisher.com. Ebioscience.com to retire in April. Get details >


Th17 Cells

CD4+ T helper cells are critical mediators of the cellular immune response. For many years, it was thought that CD4+ T helper cells existed as a dichotomy of lineages identified as Th1 and Th2 based on their expression pattern of effector cytokines. This paradigm was challenged with the demonstration that IL-17 (also known as IL-17A) was produced and secreted as a homodimer or heterodimer (with IL-17F) by a unique subset of T helper cells with the subsequent identification of ROR gamma (t) as the transcription factor responsible for specifying the lineage differentiation of Th17 cells. Th17 cell development is also driven and regulated by the expression of transcription factors STAT3, AHR, BATF, IRF4, c-Maf, IKB zeta and ROR alpha. Th17 cells play a role in host defense against extracellular pathogens and there is significant evidence that aberrant regulation of Th17 cells plays a role in the pathogenesis of multiple inflammatory and autoimmune disorders.

Suggest a new product or place a custom order.

Items 76-100 of 512

Set Descending Direction
Page:
  1. 2
  2. 3
  3. 4
  4. 5
  5. 6
25 | 50
Name Clone Application Cat. No. Reg.  

Anti-Mouse CD3e Alexa Fluor® 488

145-2C11 FC 53-0031 RUO

Anti-Mouse CD3e APC

145-2C11 FC 17-0031 RUO

Anti-Mouse CD3e APC-eFluor® 780

145-2C11 FC 47-0031 RUO

Anti-Mouse CD3e Biotin

145-2C11 FC 13-0031 RUO

Anti-Mouse CD3e eFluor® 450

145-2C11 FC 48-0031 RUO

Anti-Mouse CD3e Functional Grade Purified

145-2C11 FC, FA 16-0031 RUO

Anti-Mouse CD3e PE

145-2C11 FC 12-0031 RUO

Anti-Mouse CD3e Purified

145-2C11 FC, IHC, IHC-F, FA, IP, WB 14-0031 RUO

Anti-Mouse CD3 APC

17A2 FC 17-0032 RUO

Anti-Mouse CD3 FITC

17A2 FC, IHC, IHC-F 11-0032 RUO

Anti-Mouse CD3e Alexa Fluor® 700

eBio500A2 (500A2) FC 56-0033 RUO

Anti-Mouse CD3e APC-eFluor® 780

eBio500A2 (500A2) FC 47-0033 RUO

Anti-Mouse CD3e Biotin

eBio500A2 (500A2) FC, IHC-F 13-0033 RUO

Anti-Mouse CD3e eFluor® 450

eBio500A2 (500A2) FC 48-0033 RUO

Anti-Mouse CD3e FITC

eBio500A2 (500A2) FC 11-0033 RUO

Anti-Mouse CD3e Functional Grade Purified

eBio500A2 (500A2) FC, FA 16-0033 RUO

Anti-Mouse CD3e PE

eBio500A2 (500A2) FC 12-0033 RUO

Anti-Mouse CD3e PerCP-eFluor® 710

eBio500A2 (500A2) FC 46-0033 RUO

Anti-Mouse CD3e Purified

eBio500A2 (500A2) FC, IHC-F, FA 14-0033 RUO

Anti-Mouse CD4 Biotin

4SM95 IHC, IHC-P, WB 13-9766 RUO

Anti-Mouse CD4 eFluor® 570

4SM95 IHC, IHC-P 41-9766 RUO

Anti-Mouse CD4 eFluor® 660

4SM95 IHC, IHC-P 50-9766 RUO

Anti-Mouse CD4 Purified

4SM95 IHC, IHC-P, WB 14-9766 RUO

eZFluor™ Anti-Human CD4 FITC, CD3 PerCP-eFluor® 710, CD8a APC cocktail

SK3, SK7, SK1 FC 22-0306 RUO

eZFluor™ Anti-Human CD4 FITC and CD25 APC Cocktail

RPA-T4 (CD4) and BC96 (CD25) FC 22-0425 RUO

Items 76-100 of 512

Set Descending Direction
Page:
  1. 2
  2. 3
  3. 4
  4. 5
  5. 6
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT; Multiplex = Multiplex Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; IHC-F = Immunohistochemical Staining of Frozen Tissue Sections; IHC-P = Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; IP = Immunoprecipitation; WB = Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents