NK / NKT Cells

Natural Killer (NK) cells are important effector lymphocytes of innate immunity that exhibit cytolytic activity against a variety of allogeneic targets in a non-specific, contact-dependent, nonphagocytic process which does not require prior sensitization to antigen. NK cells share several properties with conventional cytotoxic T cells (CTL), including similar mechanisms for cytolysis. Cytolytic activity is mediated by secretion of pore-forming proteins such as Granzyme B and Perforin, serine proteases and other proteins. NK cytotoxic activity is positively regulated by IL-2, IL-15 and interferons; and is diminished by prostaglandins and TGF-beta.

Natural Killer T (NKT) cells represent a distinct lineage of T cells that express an invariant alpha/beta T cell receptor (TCR) and share a number of cell surface markers in common with NK cells. NKT cells are activated by glycolipid antigens presented by CD1d. Expression of CD160 and Valpha24Jalpha18 TCR can be used for the identification of mouse and human NKT cells, respectively.

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Name Clone Application Cat. No. Reg.  

Anti-Human Granzyme B Purified

496B ICC, IHC 14-8889 RUO

Anti-Human phospho-NF kappa B p65 (S529) Purified

MCFA30 ELISA, IHC, WB 14-9864 RUO

Anti-AIM2 Purified

Polyclonal WB 14-6008 RUO

phospho-AKT 1/2/3 (Ser473) InstantOne™ ELISA

ELISA 85-86042 RUO

AKT 1 (Total) InstantOne™ ELISA

ELISA 85-86047 RUO

AKT (Total/Phospho) InstantOne™ ELISA

ELISA 85-86046 RUO

phospho-AKT 1/2/3 (Thr308) InstantOne™ ELISA

ELISA ELISA 85-86044 RUO

AKT/ERK Activation InstantOne™ ELISA

ELISA 85-86014 RUO

ERK/AKT/p70 S6K Activation InstantOne™ ELISA

ELISA 85-86018 RUO

AKT Activation InstantOne™ ELISA

ELISA 85-86049 RUO

Anti-Human CD95 (APO-1/Fas) Purified

2R2 FC, FA BMS198* RUO

Anti-Human CD95 (APO-1/Fas) Biotin (Discontinued)

APO-1-1 FC BMS151BT* RUO

Anti-Human CD95 (APO-1/Fas) FITC

APO-1-1 FC BMS151FI* RUO

Anti-Human CD95 (APO-1/Fas) Purified

APO-1-1 FC, IHC BMS151* RUO

Human sAPO-1/Fas Platinum ELISA

ELISA BMS245* RUO

Recombinant Human sAPO-1/Fas

BMS314* RUO

Anti-Human CD95 (APO-1/Fas) Purified

SM 1-13 FC, ELISA BMS1030* RUO

Anti-Human CD95 (APO-1/Fas) Purified

SM1/1 FC, FA BMS138* RUO

Anti-Human CD95 (APO-1/Fas) Biotin

SM1/23 FC BMS140BT* RUO

Anti-Human CD95 (APO-1/Fas) FITC

SM1/23 FC BMS140FI* RUO

Anti-Human CD95 (APO-1/Fas) Purified

SM1/23 FC, FA BMS140* RUO

Anti-Human CD8a PE-Cyanine7

SK1 FC 25-0087 RUO

Anti-Human CCL3 (MIP-1 alpha) FITC

CR3M FC 11-9706 RUO

Anti-Human CCL3 (MIP-1 alpha) PE

CR3M FC 12-9706 RUO

Human MIP-1 alpha (CCL3) ELISA Ready-SET-Go!

ELISA 88-7035 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents