NK / NKT Cells

Natural Killer (NK) cells are important effector lymphocytes of innate immunity that exhibit cytolytic activity against a variety of allogeneic targets in a non-specific, contact-dependent, nonphagocytic process which does not require prior sensitization to antigen. NK cells share several properties with conventional cytotoxic T cells (CTL), including similar mechanisms for cytolysis. Cytolytic activity is mediated by secretion of pore-forming proteins such as Granzyme B and Perforin, serine proteases and other proteins. NK cytotoxic activity is positively regulated by IL-2, IL-15 and interferons; and is diminished by prostaglandins and TGF-beta.

Natural Killer T (NKT) cells represent a distinct lineage of T cells that express an invariant alpha/beta T cell receptor (TCR) and share a number of cell surface markers in common with NK cells. NKT cells are activated by glycolipid antigens presented by CD1d. Expression of CD160 and Valpha24Jalpha18 TCR can be used for the identification of mouse and human NKT cells, respectively.

Suggest a new product or place a custom order.

Items 1-25 of 120

Set Descending Direction
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
25 | 50
Name Clone Application Cat. No. Reg.  

Anti-Human CCL4 (MIP-1 beta) APC

FL34Z3L FC 17-7540 RUO

CD2 APC

RPA-2.10 8017-0029 ASR

CD2 APC

RPA-2.10 FC 9017-0029 CE

Anti-Human/Non-Human Primate CD2 APC

RPA-2.10 FC 17-0029 RUO

Anti-Human CD3 eFluor® 660

OKT3 FC 50-0037 RUO

Anti-Human CD3 Alexa Fluor® 700

OKT3 FC 56-0037 RUO

Anti-Human CD3 APC

OKT3 FC 17-0037 RUO

Anti-Human CD3 APC

SK7 FC 17-0036 RUO

CD3 APC

SK7 8017-0036 ASR

CD3 APC

SK7 FC 9017-0036 CE

Anti-Human CD3 APC-eFluor® 780

SK7 FC 47-0036 RUO

CD3 APC-eFluor® 780

SK7 FC 9047-0036 CE

CD3 APC-eFluor® 780

SK7 8047-0036 ASR

Anti-Human CD3 Alexa Fluor® 700

UCHT1 FC 56-0038 RUO

Anti-Human CD3 APC

UCHT1 FC 17-0038 RUO

Anti-Human CD3 APC-eFluor® 780

UCHT1 FC 47-0038 RUO

Anti-Human CD7 APC

4H9 FC 17-0078 RUO

CD7 APC

4H9 FC 9017-0078 CE

CD7 APC

4H9 8017-0078 ASR

Anti-Human CD7 Alexa Fluor® 700

eBio124-1D1 (124-1D1) FC 56-0079 RUO

Anti-Human CD7 APC

eBio124-1D1 (124-1D1) FC 17-0079 RUO

Anti-Human CD7 APC-eFluor® 780

eBio124-1D1 (124-1D1) FC 47-0079 RUO

CD8 APC

SK1 8017-0087 ASR

CD8 APC

SK1 FC 9017-0087 CE

CD8 APC-eFluor® 780

SK1 FC 9047-0087 CE

Items 1-25 of 120

Set Descending Direction
Page:
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
25 | 50

* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents