NK / NKT Cells

Natural Killer (NK) cells are important effector lymphocytes of innate immunity that exhibit cytolytic activity against a variety of allogeneic targets in a non-specific, contact-dependent, nonphagocytic process which does not require prior sensitization to antigen. NK cells share several properties with conventional cytotoxic T cells (CTL), including similar mechanisms for cytolysis. Cytolytic activity is mediated by secretion of pore-forming proteins such as Granzyme B and Perforin, serine proteases and other proteins. NK cytotoxic activity is positively regulated by IL-2, IL-15 and interferons; and is diminished by prostaglandins and TGF-beta.

Natural Killer T (NKT) cells represent a distinct lineage of T cells that express an invariant alpha/beta T cell receptor (TCR) and share a number of cell surface markers in common with NK cells. NKT cells are activated by glycolipid antigens presented by CD1d. Expression of CD160 and Valpha24Jalpha18 TCR can be used for the identification of mouse and human NKT cells, respectively.

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Name Clone Application Cat. No. Reg.  

Anti-Human CD7 APC

4H9 FC 17-0078 RUO

CD7 APC

4H9 FC 9017-0078 CE

CD7 APC

4H9 8017-0078 ASR

Anti-Human CD7 Alexa Fluor® 700

eBio124-1D1 (124-1D1) FC 56-0079 RUO

Anti-Human CD7 APC

eBio124-1D1 (124-1D1) FC 17-0079 RUO

Anti-Human CD7 APC-eFluor® 780

eBio124-1D1 (124-1D1) FC 47-0079 RUO

CD8 APC

SK1 FC 9017-0087 CE

CD8 APC

SK1 8017-0087 ASR

CD8 APC-eFluor® 780

SK1 FC 9047-0087 CE

CD8 APC-eFluor® 780

SK1 8047-0087 ASR

Anti-Mouse CD8a Alexa Fluor® 700

53-6.7 FC 56-0081 RUO

Anti-Mouse CD8a APC

53-6.7 FC 17-0081 RUO

Anti-Mouse CD8a APC-eFluor® 780

53-6.7 FC 47-0081 RUO

Anti-Mouse CD8a Cyanine5

53-6.7 FC 19-0081 RUO

Anti-Mouse CD8a eFluor® 660

53-6.7 FC, IHC 50-0081 RUO

Anti-Human CD8a Alexa Fluor® 700

OKT8 (OKT-8) FC 56-0086 RUO

Anti-Human CD8a APC

OKT8 (OKT-8) FC 17-0086 RUO

Anti-Rat CD8a APC

OX8 FC 17-0084 RUO

Anti-Human CD8a Alexa Fluor® 700

RPA-T8 FC 56-0088 RUO

Anti-Human CD8a APC

RPA-T8 FC 17-0088 RUO

Anti-Human CD8a APC-eFluor® 780

RPA-T8 FC 47-0088 RUO

Anti-Human CD8a APC

SK1 FC 17-0087 RUO

Anti-Human CD8a APC-eFluor® 780

SK1 FC 47-0087 RUO

Anti-Canine CD8a APC

YCATE55.9 FC 17-5080 RUO

Anti-Mouse CD8b APC

eBioH35-17.2 (H35-17.2) FC 17-0083 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents