NK / NKT Cells

Natural Killer (NK) cells are important effector lymphocytes of innate immunity that exhibit cytolytic activity against a variety of allogeneic targets in a non-specific, contact-dependent, nonphagocytic process which does not require prior sensitization to antigen. NK cells share several properties with conventional cytotoxic T cells (CTL), including similar mechanisms for cytolysis. Cytolytic activity is mediated by secretion of pore-forming proteins such as Granzyme B and Perforin, serine proteases and other proteins. NK cytotoxic activity is positively regulated by IL-2, IL-15 and interferons; and is diminished by prostaglandins and TGF-beta.

Natural Killer T (NKT) cells represent a distinct lineage of T cells that express an invariant alpha/beta T cell receptor (TCR) and share a number of cell surface markers in common with NK cells. NKT cells are activated by glycolipid antigens presented by CD1d. Expression of CD160 and Valpha24Jalpha18 TCR can be used for the identification of mouse and human NKT cells, respectively.

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Name Clone Application Cat. No. Reg.  

Anti-Human CD95 (APO-1/Fas) Biotin

APO-1-1 FC BMS151BT* RUO

Human sAPO-1/Fas Platinum ELISA

ELISA BMS245* RUO

Anti-Human CD95 (APO-1/Fas) Biotin

SM1/23 FC BMS140BT* RUO

Anti-Human/Non-Human Primate CD2 Biotin

RPA-2.10 FC 13-0029 RUO

Anti-Human CD3 Biotin

OKT3 FC 13-0037 RUO

Anti-Human CD3 Biotin

UCHT1 FC 13-0038 RUO

Anti-Human CD7 Biotin

eBio124-1D1 (124-1D1) FC 13-0079 RUO

Anti-Human CD8a Biotin

HIT8a FC 13-0089 RUO

Anti-Human CD8a Biotin

OKT8 (OKT-8) FC 13-0086 RUO

Anti-Human CD11b Biotin

ICRF44 FC 13-0118 RUO

Anti-Human CD16 Biotin

eBioCB16 (CB16) FC 13-0168 RUO

Human sCD26 Platinum ELISA

ELISA BMS235* RUO

Anti-Human CD26 Biotin

M-A261 FC BMS143BT* RUO

Human sCD27 Instant ELISA

ELISA BMS286INST* RUO

Anti-CD27 Biotin

LG.7F9 FC 13-0271 RUO

Anti-Human CD27 Biotin

O323 FC 13-0279 RUO

Anti-Human CD31 (PECAM-1) Biotin

WM-59 (WM59) FC 13-0319 RUO

Anti-Human CD38 Biotin

HIT2 FC 13-0389 RUO

Human sCD40 Platinum ELISA

ELISA BMS265* RUO

Anti-Human CD45 Biotin

CD45-2B11 IHC 13-9457 RUO

Anti-Human CD45 Biotin

HI30 FC 13-0459 RUO

Anti-Human CD56 (NCAM) Biotin

CMSSB FC, IHC 13-0567 RUO

Anti-Human CD69 Biotin

FN50 FC 13-0699 RUO

Anti-Human CD71 (Transferrin Receptor) Biotin

OKT9 (OKT-9) FC 13-0719 RUO

Anti-Human CD85j (ILT2) Biotin

HP-F1 FC 13-5129 RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents