NK / NKT Cells

Natural Killer (NK) cells are important effector lymphocytes of innate immunity that exhibit cytolytic activity against a variety of allogeneic targets in a non-specific, contact-dependent, nonphagocytic process which does not require prior sensitization to antigen. NK cells share several properties with conventional cytotoxic T cells (CTL), including similar mechanisms for cytolysis. Cytolytic activity is mediated by secretion of pore-forming proteins such as Granzyme B and Perforin, serine proteases and other proteins. NK cytotoxic activity is positively regulated by IL-2, IL-15 and interferons; and is diminished by prostaglandins and TGF-beta.

Natural Killer T (NKT) cells represent a distinct lineage of T cells that express an invariant alpha/beta T cell receptor (TCR) and share a number of cell surface markers in common with NK cells. NKT cells are activated by glycolipid antigens presented by CD1d. Expression of CD160 and Valpha24Jalpha18 TCR can be used for the identification of mouse and human NKT cells, respectively.

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Name Clone Application Cat. No. Reg.  

Human Cardiovascular 6plex FlowCytomix Multiplex

Multiplex BMS811/2FF* RUO

Human Chemokine 6plex FlowCytomix Multiplex

Multiplex BMS813FF* RUO

Mouse Chemokine 6plex FlowCytomix Multiplex

Multiplex BMS821FF* RUO

Mouse CXCL1/KC FlowCytomix Simplex

Multiplex BMS86019FF* RUO

Rat Cytokines 5plex FlowCytomix Multiplex

Multiplex BMS826FF* RUO

Rat IFN gamma FlowCytomix Simplex

Multiplex BMS8621/3FF* RUO

Human IFN gamma FlowCytomix Simplex

Multiplex BMS8228FF* RUO

Mouse IFN-gamma FlowCytomix Simplex

Multiplex BMS8606/2FF* RUO

Mouse IL-15/IL-15R FlowCytomix Simplex

Multiplex BMS86023FF* RUO

Human IL-18 FlowCytomix Simplex

Multiplex BMS8267FF* RUO

Mouse IL-18 FlowCytomix Simplex

Multiplex BMS8618FF* RUO

Human sL-selectin FlowCytomix Simplex

Multiplex BMS80206FF* RUO

Mouse MIP-1 alpha FlowCytomix Simplex

Multiplex BMS86013FF* RUO

Human MIP-1 alpha FlowCytomix Simplex

Multiplex BMS82029FF* RUO

Human MIP-1 beta FlowCytomix Simplex

Multiplex BMS82030FF* RUO

Mouse MIP-1 beta FlowCytomix Simplex

Multiplex BMS86014FF* RUO

Human Obesity 9plex FlowCytomix Multiplex

Multiplex BMS816/2FF* RUO

Human sCD40L FlowCytomix Simplex

Multiplex BMS8239/2FF* RUO

Mouse Th1/Th2 10plex Ready-to-Use FlowCytomix Multiplex

Multiplex BMS820FFRTU* RUO

Mouse Th1/Th2 10plex FlowCytomix Multiplex

Multiplex BMS820FF* RUO

Human Th1/Th2 11plex FlowCytomix Multiplex

Multiplex BMS810FF* RUO

Human Th1/Th2 11plex Ready-to-Use FlowCytomix Multiplex

Multiplex BMS810FFRTU* RUO

Human Th1/Th2/Th9/Th17/Th22 13plex FlowCytomix Multiplex

Multiplex BMS817FF* RUO

Mouse Th1/Th2/Th17/Th22 13plex FlowCytomix Multiplex

Multiplex BMS822FF* RUO

Mouse TNF-alpha FlowCytomix Simplex

Multiplex BMS8607/2FF* RUO

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* = Please click on product link to see all available sizes and pricing.

FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents