Monocytes / Macrophages

Monocytes are white blood cells that originate in the bone marrow and travel through the bloodstream to tissues throughout the body where they mature and differentiate into tissue-specific macrophages. Monocytes and macrophages are phagocytes that act in both a non-specific defense mode (innate immunity) and help to initiate specific defense mechanisms (adaptive immunity). Macrophages are professional antigen-presenting cells (APCs). After digesting a pathogen, a macrophage displays a fragment of the antigen to a corresponding helper T cell. In addition, monocytes and macrophages release substances including enzymes, complement proteins and regulatory factors that stimulate other cells of the immune system.

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Anti-Mouse/Rat TNF alpha PE-Cyanine7

TN3-19 FC, ELISA, FA 25-7423 RUO

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FC = Flow Cytometry, Intracellular Staining/Flow Cytometry; ELISA = ELISA, ELISPOT, Multiplexing Immunoassays; ICC = Immunocytochemistry; IHC = Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging; FA = Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation; WB = Immunoprecipitation, Western Blotting

RUO = Research Use Only; GPR = General Purpose Reagent; ASR = Analyte Specific Reagent. Analytical and performance characteristics are not established; CE = CE-marked reagents