CD79a PerCP-Cy5.5

Also known as: mb-1

Clone: HM47

CE

SKU# 9045-0792

Cat. No.	Size
9045-0792-025	25 tests
9045-0792-120	120 tests
Please inquire about custom configurations or bulk packaging.

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'Fluorescence profiles of normal human peripheral blood lymphocytes unstained (blue histogram) or...View More

Description

Description: The monoclonal antibody HM47 recognizes the cytoplasmic domain of CD79a, also known as mb-1. CD79a is a 47 kDa membrane glycoprotein that associates with CD79b to form the heterodimeric B cell receptor (BCR). This receptor is responsible for B cell signaling, resulting in activation, apoptosis or anergy. Expression of CD79a is found throughout development from the earliest pre-B cell to plasma cells. CD79 is expressed on B cell neoplasms and some non-B cell malignancies such as AML. Unlike other antibodies that can be masked in B cell neoplastic cells, HM47 is a reliable antibody for recognizing CD79a and, as such, is a good marker for B cells.

Details

Host	Mouse
Isotype	IgG1, kappa
Reactivity	Human
Conjugate	PerCP-Cyanine5.5
Laser	Blue Laser
Emit	690 nm
Excite	488 nm
Legal	For research (not to include in vivo research) and/or in vitro diagnostic use only. The only permitted commercial use is provision of research (not to include in vivo research) services and/or in vitro diagnostic services. Not for therapeutic or in vivo applications. Other use needs licenses which are available from GE Healthcare Bio-Sciences Corp. Under U.S. patent nos. Nos 5,268,486, 5,569,587 and 5,627,027 and foreign equivalents and pending applications. This product is subject to proprietary rights of GE Healthcare Bio-Sciences Corp. (“GE Healthcare”) and Carnegie Mellon University (“CMU”) and made and sold under license from GE Healthcare. The product bearing this label is licensed for sale only for research (not to include in vivo research) and in addition may be used to perform research (not to include in vivo research) and/or in vitro diagnostic services for third parties. It is not licensed nor are there any implied licenses for any other use including, without limitation, commercial uses unless expressly authorized by GE Healthcare in writing. If you intend to use this product commercially and you do not have a license to use this product for the intended commercial purpose, return this product, unopened to eBioscience, Inc. 10255 Science Center Drive, San Diego, California 92121 USA and any money paid for the product will be refunded.
Reported Applications	Flow Cytometric Analysis

Documentation

Instructions for Use (English)	Download English IFU
Instructions for Use (French)	Download French IFU
Instructions for Use (German)	Download German IFU
Instructions for Use (Italian)	Download Italian IFU
Instructions for Use (Spanish)	Download Spanish IFU

Additional Formats

Cat. No.	Name	Excite	Emit	Application	Reg.
9012-0792	CD79a PE	488 nm	575 nm	FC	CE
9046-0792	CD79a PerCP-eFluor® 710	488 nm	710 nm	FC	CE

References

References: Procedures for the Collection of Diagnostic Blood Specimens by Venipuncture (H3-A6), 3rd Edition published by the National Committee for Clinical Laboratory Standards.

Schlossman SF, Boumsell L, Gilks W, et al, eds. Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 1995.

Sakaguchi N, et al. B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties. EMBO J. 1988;7:3457-3464.

View More Products

Antigens	Cell Type	Formats
CD79a	B Cells	PerCP-Cyanine5.5