Anti-Canine CD90 (Thy-1) PE

Description: This YKIX337.217 monoclonal antibody reacts with canine CD90, which is also known as Thy-1. This 25-37 kDa N-glycoylsated cell adhesion molecule is expressed on thymocytes, peripheral T cells, some B cells, monocytes, and granulocytes albeit at a lower level. CD90 is also expressed on cells in the bone marrow, brain, and kidney, as well as on mesenchymal stem cells.

This monoclonal antibody has been reported to deplete cells in vitro and in vivo.

References: Kang JW, Kang KS, Koo HC, Park JR, Choi EW, Park YH. Soluble factors-mediated immunomodulatory effects of canine adipose tissue-derived mesenchymal stem cells. Stem Cells Dev. 2008 Aug;17(4):681-93.

Cobbold S, Metcalfe S. Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW). Tissue Antigens. 1994 Mar;43(3):137-54. (YKIX337.217, FC)

McKenzie JL, Fabre JW. Studies with a monoclonal antibody on the distribution of Thy-1 in the lymphoid and extracellular connective tissues of the dog. Transplantation. 1981 Apr;31(4):275-82.